ID Q5CQT6_CRYPI Unreviewed; 1326 AA.
AC Q5CQT6;
DT 12-APR-2005, integrated into UniProtKB/TrEMBL.
DT 12-APR-2005, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Neutral sphingomyelinase activation associated factor-like BEACH domain containing protein {ECO:0000313|EMBL:EAK87786.1};
GN ORFNames=cgd4_3390 {ECO:0000313|EMBL:EAK87786.1};
OS Cryptosporidium parvum (strain Iowa II).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=353152 {ECO:0000313|EMBL:EAK87786.1, ECO:0000313|Proteomes:UP000006726};
RN [1] {ECO:0000313|EMBL:EAK87786.1, ECO:0000313|Proteomes:UP000006726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Iowa II {ECO:0000313|Proteomes:UP000006726};
RX PubMed=15044751; DOI=10.1126/science.1094786;
RA Abrahamsen M.S., Templeton T.J., Enomoto S., Abrahante J.E., Zhu G.,
RA Lancto C.A., Deng M., Liu C., Widmer G., Tzipori S., Buck G.A., Xu P.,
RA Bankier A.T., Dear P.H., Konfortov B.A., Spriggs H.F., Iyer L.,
RA Anantharaman V., Aravind L., Kapur V.;
RT "Complete genome sequence of the apicomplexan, Cryptosporidium parvum.";
RL Science 304:441-445(2004).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAK87786.1}.
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DR EMBL; AAEE01000008; EAK87786.1; -; Genomic_DNA.
DR RefSeq; XP_625916.1; XM_625916.1.
DR STRING; 353152.Q5CQT6; -.
DR EnsemblProtists; EAK87786; EAK87786; cgd4_3390.
DR GeneID; 3372871; -.
DR KEGG; cpv:cgd4_3390; -.
DR VEuPathDB; CryptoDB:cgd4_3390; -.
DR InParanoid; Q5CQT6; -.
DR OrthoDB; 47483at2759; -.
DR Proteomes; UP000006726; Chromosome 4.
DR CDD; cd06071; Beach; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR023362; PH-BEACH_dom.
DR PANTHER; PTHR13743:SF112; BEACH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR Pfam; PF02138; Beach; 1.
DR SMART; SM01026; Beach; 1.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006726}.
FT DOMAIN 190..299
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 342..674
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REGION 1031..1052
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1033..1052
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1326 AA; 152633 MW; 87CEEF697D7A087B CRC64;
MALKGVRQFS HLTLEENEEY VADVSCVCKA TGIQIKTFGS VLKGRIRIGS KSIIIEPDDS
TITMIKILFS QITDMKLDFS NSKMIIFTKV VRLVDVQVID GKSRSVTPNQ VLSSKDCRGL
ESNRDSFELE ITITSEIAQH LMNLSSELWM EHSKKHGSSN KLEDLVGKWI SFLYNKEILN
VEYEFLLDHR DQFLISKPLI VNRIKPFTKH RGILHIVSSG ICFKPLPNFS NKPYKRIPLK
NIWFIFKRIY SMKPNSVEII YGKELKPHIM TCKGRTNWRS LFLEFQSTQD REHIVAFLQS
YLMSLNSKGF QWSSHVPQYA SCLCSSHNTS SCLPMLFVDP LYASQSPCFK NHIQNLWIHG
SISTYHYLDY LNSISGRSKG DLTQYPIFPW TIVSFNSVLN SRHDLSQSFN YRDLSKPLGS
ININNLEMLK SRMKDLPASE QFLYGSHYST PGYISYYLVR QFPEYQLKLH GGDFDVWNRM
FHSMNDTWRT ILEGKTTYME LIPQFYEQNP DFLLNNKLNI RTNSGSLLNV QIPNWELETG
QNQFNASTLN TANLSQAETF LRTMRYALEG QVVSQHIHEW IDLIFGFKQR GPQAYSSDNL
FHPITYINSS IAMMNDKSPV YAVQEYNNEG ISNIQQEIYT RRTIDENEDI ALKAQVEEFG
QVPIMLFNEP HPKRGITSFE ESTIMQHLNH ECANMPWFVL FKSNPQLLEA KYDFNQKLDQ
QKHEESYLEK GIVSSSLLDL QSHLKPVKAL NSEFSNTTNR MDALKRDIVS QENILRSNYK
LGKDEFDNSK EKFTLDENNG FMLLFTEDYC NFKGGFQKLD LSKIIQLQES ANSKTQFTFL
TSIYERPGEF VLLALLDQFE ERLLFYISVY GFEELGFKCI YSSKQDLFEN KAICIDLLVC
NEGSAYVTIG TLSGDLIYLR FKLSNKASTY NLTNSEHGFN NIFVMAQKEK VLKQFNMGNV
SLLFSIEFHQ SDCYIVAVSQ GGIMLVSKHS IDNRQDFRKS IWFPIVDIPL RYEKVSSIIQ
MDLVNPELQS LHMDSPENHK NHRSPDRSTS RFGKITKDID SSGFCFSCIL SDLGGKKQRL
WSFGGQDKLL SLDLIGMLNS VFSVQGNSRK ENGGNINNNL SNDVITIESG SGNPQSFGLK
DIEESQKVEW IFLKEKNLVL YVGFNSPGNL TILVFWDIQK KVDAKVHKVI FIPSLFTESV
CWDKYRKGLL ILGRQISNAD TKSQLQTEDK TGSSQSINNE EGNIYFLQER HWTSKNNNAL
QILTLKSSFE LLLNMNIRRT FSLDHNSPDF KRSTIKCTEK LIILNSYLAF LVFKISKKNQ
TTENLG
//
