ID Q5CRN8_CRYPI Unreviewed; 1803 AA.
AC Q5CRN8;
DT 12-APR-2005, integrated into UniProtKB/TrEMBL.
DT 12-APR-2005, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=Sister chromatid cohesion protein {ECO:0000256|RuleBase:RU364107};
GN ORFNames=cgd5_2080 {ECO:0000313|EMBL:EAK88061.1};
OS Cryptosporidium parvum (strain Iowa II).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=353152 {ECO:0000313|EMBL:EAK88061.1, ECO:0000313|Proteomes:UP000006726};
RN [1] {ECO:0000313|EMBL:EAK88061.1, ECO:0000313|Proteomes:UP000006726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Iowa II {ECO:0000313|Proteomes:UP000006726};
RX PubMed=15044751; DOI=10.1126/science.1094786;
RA Abrahamsen M.S., Templeton T.J., Enomoto S., Abrahante J.E., Zhu G.,
RA Lancto C.A., Deng M., Liu C., Widmer G., Tzipori S., Buck G.A., Xu P.,
RA Bankier A.T., Dear P.H., Konfortov B.A., Spriggs H.F., Iyer L.,
RA Anantharaman V., Aravind L., Kapur V.;
RT "Complete genome sequence of the apicomplexan, Cryptosporidium parvum.";
RL Science 304:441-445(2004).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU364107}.
CC -!- SIMILARITY: Belongs to the SCC2/Nipped-B family.
CC {ECO:0000256|RuleBase:RU364107}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAK88061.1}.
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DR EMBL; AAEE01000007; EAK88061.1; -; Genomic_DNA.
DR RefSeq; XP_626148.1; XM_626148.1.
DR STRING; 353152.Q5CRN8; -.
DR EnsemblProtists; EAK88061; EAK88061; cgd5_2080.
DR GeneID; 3373260; -.
DR KEGG; cpv:cgd5_2080; -.
DR VEuPathDB; CryptoDB:cgd5_2080; -.
DR InParanoid; Q5CRN8; -.
DR OMA; HANNETE; -.
DR OrthoDB; 198696at2759; -.
DR Proteomes; UP000006726; Chromosome 5.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061780; P:mitotic cohesin loading; IEA:InterPro.
DR GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR CDD; cd15489; PHD_SF; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024986; Nipped-B_C.
DR InterPro; IPR033031; Scc2/Nipped-B.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR21704:SF18; NIPPED-B-LIKE PROTEIN; 1.
DR PANTHER; PTHR21704; NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED; 1.
DR Pfam; PF12830; Nipped-B_C; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|RuleBase:RU364107};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364107};
KW Reference proteome {ECO:0000313|Proteomes:UP000006726};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU364107};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 471..522
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 609..628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1330..1349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1759..1803
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 442..469
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1786..1803
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1803 AA; 205809 MW; 9CB169441428B892 CRC64;
MELPSQLKKS NACTIMNDNN EQTNKTDANW KRRPSSNKGT EHFTAIFDVL LQDKAPKLSE
FNKMNLKKVQ LEISKFDNQI LHEFCGRIEF SRNCEALLEE ILCSDLIIEF GKRISSKDRG
KGSENVLIEN LVNVINIVGI FLYFELVIFN EMTFSKEIRI ISNIIRSVLP IIFSESIKNC
RLEAFNTSFI GCLEAINTIV RTKSIHEIFS TQIIVGLLSI FLIEDSNTMV VFLTTEIVVH
LFVSGSLNSN EFLENSLNLI FDVMEELPHT NKAIKKAKVC IEMDSYMHIY VYLLLRLIQS
ICIPNGIVSS DNIHSIQNIS MKHHNLAKFI CNQFATFFIN SIILKRTKRK ESNFSTGNDI
ATVILTDLLK ASFNPKYNIC STITQIIIVQ LIKISNNSLI NEAGPKSQSI NIDLYSKELC
IHLLGASLSI IYKNVNVKLM CIDSSEKSID ESKSEIKDAQ IERDDATNNV IIDCICDKLY
SIYTEKLLRC ESCGRNFHLD CIRNGTYLEI YEQWKCDSCT INLIFDEINM NFGINGEEIL
SKNSELTVVL IIVLEYLYRK TAMTVSQASS EPVTIDITQL VTDSGSSVAC SFILEMIAKL
KLGNKNLEKA DGKEESKNKT TKNGSRKLSQ TCNEISQLYT MLLTEWVSPI TKVHSPLIAY
SSKFPKLLEA NVIRFWNRIL AKELKNVANI ILHCLLSNIY NSTITSMRRI SLNSVGQIIS
VKPNLLITNE TVLNAIILSL KDKTPKVRER ALAIIEKYFS DILTNETSDF TYDGENSKIV
FDRVTKLLLE QIFRTAYDIS PLVRMTSVRI LRALYQHDPS KLNIGIILLK RASAVEETQS
IRRLIFDSFT SIWFHNSSKV NESMAECLVK LINYSESNEF LQYINHDQKS TNCLLKGVMS
ILQENQSIKN LEALITRWSN ILVDMFIQSD NYRDTIKSEK LVSEEIGLKN EQLNDQGIAN
NNSSRDFSET KLQILKTAEV IGKVYPKSIK EMYSYIVVYL KDFRQYKSEV MVHICTVLSY
ILPHVGDLEV ETIEFDLLKI TTNSRSPQLI RSSILCLCNL LMQNEKGLNE NNTLSPLILD
NIRVLWDYRQ KTLGMEVTMD LKEVDQLRRS AWLLGCIFEF SSPNMALAIV DNKLERAKVI
QTEFGISWTL ESCSTNKIPK SEFGEDLGFE YTILESNKII FDLLCDLYYI LDWNLNKGVL
FPTLIQFLMN QKQFVKTLKF NNLIKCAIKG DKSLANLDCQ SKLSIQCSNI TANNSKANSN
LCIICLQGIL SLLKNYELQA LKENKIAQEN DLEQTKRVNI TEDMTNQFHD EINQCDDSFS
GNNNIFITPN TNKRTSVHSE KNEINSPVSS SSYSNLENIS SIRTSVFGSV THNTSSVSAS
QPIASNLELL LNLFQETTGF QEGRFSNQQK QQVSSLILCI LEQLNKQGLV NPTSIIPHVS
GLLFSSNREV SFKSYQIISS LFERFPNLII NKYKEISLYG FVFCTSNFPG LLGVYNSKTD
SENVLRSIIS NDIVNDKIQS KSRPEVLETV FEFFTRIYSE KCRTKRVFRE SIIRGCCKQL
ELLLSIDETE ILLKKLKLHL MLEKKVLLVL YMEFISYILL AMPFQFESEI LLVLFCLGEI
CVNCSQNLHN DSESSVKIDK EQAFCSAILV TVCTTVQLIL KEEYRISENQ ISSFNPYNSI
NKEKPKFSHQ DSELNVGIIE NSTNIVSLGA GTMYELLQSL REKLHIIWEI SEGCDSEKKL
LDYSNEIIYF YTQTTSEKVS KHTRGKHTKR KQNKRNRERE EEYSDASSTQ SWSPSSRISK
SRK
//
