ID Q5CS12_CRYPI Unreviewed; 732 AA.
AC Q5CS12;
DT 12-APR-2005, integrated into UniProtKB/TrEMBL.
DT 12-APR-2005, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Extracellular protein with a ricin domain and a family 2 glycosyltransferase domain {ECO:0000313|EMBL:EAK88160.1};
GN ORFNames=cgd5_690 {ECO:0000313|EMBL:EAK88160.1};
OS Cryptosporidium parvum (strain Iowa II).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=353152 {ECO:0000313|EMBL:EAK88160.1, ECO:0000313|Proteomes:UP000006726};
RN [1] {ECO:0000313|EMBL:EAK88160.1, ECO:0000313|Proteomes:UP000006726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Iowa II {ECO:0000313|Proteomes:UP000006726};
RX PubMed=15044751; DOI=10.1126/science.1094786;
RA Abrahamsen M.S., Templeton T.J., Enomoto S., Abrahante J.E., Zhu G.,
RA Lancto C.A., Deng M., Liu C., Widmer G., Tzipori S., Buck G.A., Xu P.,
RA Bankier A.T., Dear P.H., Konfortov B.A., Spriggs H.F., Iyer L.,
RA Anantharaman V., Aravind L., Kapur V.;
RT "Complete genome sequence of the apicomplexan, Cryptosporidium parvum.";
RL Science 304:441-445(2004).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAK88160.1}.
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DR EMBL; AAEE01000007; EAK88160.1; -; Genomic_DNA.
DR RefSeq; XP_626024.1; XM_626024.1.
DR AlphaFoldDB; Q5CS12; -.
DR STRING; 353152.Q5CS12; -.
DR EnsemblProtists; EAK88160; EAK88160; cgd5_690.
DR GeneID; 3373167; -.
DR KEGG; cpv:cgd5_690; -.
DR VEuPathDB; CryptoDB:cgd5_690; -.
DR InParanoid; Q5CS12; -.
DR OMA; CAYDHYK; -.
DR OrthoDB; 202750at2759; -.
DR Proteomes; UP000006726; Chromosome 5.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR11675; N-ACETYLGALACTOSAMINYLTRANSFERASE; 1.
DR PANTHER; PTHR11675:SF43; POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 1; 1.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR Pfam; PF00652; Ricin_B_lectin; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Lectin {ECO:0000256|ARBA:ARBA00022734}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006726};
KW Transferase {ECO:0000313|EMBL:EAK88160.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 592..717
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|SMART:SM00458"
SQ SEQUENCE 732 AA; 83344 MW; 456F718D753DF536 CRC64;
MSQTNIFRRF FRRIHYQLGR AFVCRNKLLY LVLVIILLWA LSFTIVHQLV ISSTGNYMSS
SVSKSLRGIS GRGMKVFRCL IKGNCINTTN EDINVDFMKL VGESDSRHQS YIIKLRTMPD
KYNLTNYGNV RNLTESTAIT KYFDNLAFAS PEDTGIDYNT DLGLTLVKLY DLGSKLLPYI
EHKEYSALFS NTSSQYLNSL AVFPGYNDLR QHGILGIFPN GTTPFAFIEK PPEINKNNEE
SFLAKGGGFN RQLSDFLSLD RVPLEVRDPI CRNMIYPIKD LDDASVIITF YNEPLSTLLR
SVHSVLNNTP PPLLREIILV NDGSDMIDLV PGGFLDDYIR LLPKVRVVHL TERKGIVGAR
LSGVRAASAP VIVILDSHIE TSRQWLEPQL LRLKESPKSV VMPQIDSIDP VNFAFSNFSG
IGCRLGFKYS ILEQATLTGP INDTTPIKSP VMAGGLFAMK RDYFWHLGGY DEKFRHWGAE
NVEISFRIWM CGGQIECTPC SRVFHIFRKK GVGYSSPPES LWHNRLRTAR VWMDEFYQIT
EMLAPNPNIK LGSFDDMLHL KKKLKCKPFR WFLDNVAPET YITQLDHLLF VGEIRNKKLD
NICLDSMGGQ TDGDKIGVFH CHGKKGTQAF MMSNHTQQIR IVSKESYCIG SNLKYAACSN
SEMTNVWRLE NEMIKANVEP NKYVCLSLTE DNDSSTKHKA ELLDCDPNDP SQHWNVNKFK
PKKYIPLKLS YM
//
