ID   Q5CUG3_CRYPI            Unreviewed;       476 AA.
AC   Q5CUG3;
DT   12-APR-2005, integrated into UniProtKB/TrEMBL.
DT   12-APR-2005, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=Probable phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthase, 2x SMART_PLDc domains, possible bacterial origin {ECO:0000313|EMBL:EAK89258.1};
DE   Flags: Fragment;
GN   ORFNames=cgd3_2940 {ECO:0000313|EMBL:EAK89258.1};
OS   Cryptosporidium parvum (strain Iowa II).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX   NCBI_TaxID=353152 {ECO:0000313|EMBL:EAK89258.1, ECO:0000313|Proteomes:UP000006726};
RN   [1] {ECO:0000313|EMBL:EAK89258.1, ECO:0000313|Proteomes:UP000006726}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Iowa II {ECO:0000313|Proteomes:UP000006726};
RX   PubMed=15044751; DOI=10.1126/science.1094786;
RA   Abrahamsen M.S., Templeton T.J., Enomoto S., Abrahante J.E., Zhu G.,
RA   Lancto C.A., Deng M., Liu C., Widmer G., Tzipori S., Buck G.A., Xu P.,
RA   Bankier A.T., Dear P.H., Konfortov B.A., Spriggs H.F., Iyer L.,
RA   Anantharaman V., Aravind L., Kapur V.;
RT   "Complete genome sequence of the apicomplexan, Cryptosporidium parvum.";
RL   Science 304:441-445(2004).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAK89258.1}.
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DR   EMBL; AAEE01000004; EAK89258.1; -; Genomic_DNA.
DR   RefSeq; XP_626851.1; XM_626851.1.
DR   AlphaFoldDB; Q5CUG3; -.
DR   STRING; 353152.Q5CUG3; -.
DR   EnsemblProtists; EAK89258; EAK89258; cgd3_2940.
DR   GeneID; 3373773; -.
DR   KEGG; cpv:cgd3_2940; -.
DR   InParanoid; Q5CUG3; -.
DR   OMA; WLNFEVT; -.
DR   OrthoDB; 276053at2759; -.
DR   Proteomes; UP000006726; Chromosome 3.
DR   GO; GO:0030572; F:phosphatidyltransferase activity; IEA:UniProt.
DR   GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:UniProt.
DR   CDD; cd09110; PLDc_CLS_1; 1.
DR   CDD; cd09159; PLDc_ybhO_like_2; 1.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR   InterPro; IPR025202; PLD-like_dom.
DR   InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR   PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR   PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR   Pfam; PF13091; PLDc_2; 2.
DR   SMART; SM00155; PLDc; 2.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR   PROSITE; PS50035; PLD; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006726};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          173..199
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EAK89258.1"
SQ   SEQUENCE   476 AA;  55685 MW;  7FEE5B3B301A2AB5 CRC64;
     ACKEIPYFFF LMKRKDKNEI INTNYIASKP WLAEEVNNRL KERDNIFNVC EDEFESNKWF
     QLMNKFSKYG EITRGNKIKL FENSRDSYLS MIESIDSAKK RVWFETYIFE ECETGEKFVD
     SFCEASQRGC EVILLLDAFG SSKFPKRWEQ KLLKNNVKVI WFNPISQIFK DTFLFRNHRK
     LLIADEKAYC GSINITNRIN DSSLNDEANI KNYNIICNSA YKKLIFLFKQ VIYSISPIKV
     NKLCFYDVHA EIEGPATYDL GKVFIDSLKE SKCGQIPIIF QRPKEIKNGT ILQVLYSNTR
     RQHRGIQNVL NIATKNSNSY IYLTTSYFFP PSFLRRAIQT AINNNVKVSM LLSGRSDIPG
     DTIATKYLIK RFIQNNVRFF FTRNIHCHAK YITIDGIWSS FGSFNWDGFS ANRNLEVSVA
     SFDSKIASQL MKMHSKMTHS FQSTEQTINQ WNEQSRLTRV CSKAAYMLIK FVNKYL
//