ID Q5E4N6_ALIF1 Unreviewed; 482 AA.
AC Q5E4N6;
DT 15-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 2.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN OrderedLocusNames=VF_1515 {ECO:0000313|EMBL:AAW86010.2};
OS Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Aliivibrio.
OX NCBI_TaxID=312309 {ECO:0000313|EMBL:AAW86010.2, ECO:0000313|Proteomes:UP000000537};
RN [1] {ECO:0000313|EMBL:AAW86010.2, ECO:0000313|Proteomes:UP000000537}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700601 / ES114 {ECO:0000313|Proteomes:UP000000537};
RX PubMed=15703294; DOI=10.1073/pnas.0409900102;
RA Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R.,
RA Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E.,
RA Stevens A., Visick K., Whistler C., Greenberg E.P.;
RT "Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with
RT pathogenic congeners.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005).
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DR EMBL; CP000020; AAW86010.2; -; Genomic_DNA.
DR RefSeq; YP_204898.2; NC_006840.2.
DR AlphaFoldDB; Q5E4N6; -.
DR STRING; 312309.VF_1515; -.
DR DNASU; 3278777; -.
DR EnsemblBacteria; AAW86010; AAW86010; VF_1515.
DR KEGG; vfi:VF_1515; -.
DR PATRIC; fig|312309.11.peg.1532; -.
DR eggNOG; COG3614; Bacteria.
DR eggNOG; COG3706; Bacteria.
DR HOGENOM; CLU_041147_0_0_6; -.
DR OrthoDB; 6572677at2; -.
DR Proteomes; UP000000537; Chromosome I.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:UniProt.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.350; CHASE domain; 1.
DR InterPro; IPR006189; CHASE_dom.
DR InterPro; IPR042240; CHASE_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF03924; CHASE; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM01079; CHASE; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50839; CHASE; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000537};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 283..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 127..268
FT /note="CHASE"
FT /evidence="ECO:0000259|PROSITE:PS50839"
FT DOMAIN 352..482
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 482 AA; 55479 MW; AEFB55AA5FCCEB60 CRC64;
MRFVYLSDLD NNQKNFYKEA DRQSALLSML IEKDIDFIGA GANFYQVGSK KDWSQFPLFA
DSLLHRSNSL ISLQWMEKVE EKDIDEHFQQ IHKNYPLAKL YTVPKDQPKT YGYVMKNHEP
IYIATDIYPR DEKNTPLIGF YSSRERFNLV VEEFLTTGRP SVSDKIRLLQ DSLDQSAQKT
GMLVYHPVFT SDKTALKGVM VGVVRITSYF DRLVNSTSLG EELVVRIIDT GFDAGDDPIM
YQSSTWNNFK GVDYTTSVKI ENRLWKIEYK SDNKLNEYQR LTLIWLFFGI LTISMLIAAL
TSVVTRDKQR IENLLEIRTK ELRYMAMHDD LTGLLNRRAI RDVITRYIEA EKPFALLCFD
IDKFKQINDT YGHPEGDEVL RHIGHLMSET LGNNVHVSRL GGDEFSIVLK LNNIDELTLI
SEQIHDLVAT SPTVFNDFEI AQTISLGAVL WQGETLEELL KAADQALYQS KTMGRNQVTI
RG
//
