ID Q5EP42_9VIRU Unreviewed; 1869 AA.
AC Q5EP42;
DT 15-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 129.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
OS Banana streak MY virus.
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Ortervirales; Caulimoviridae; Badnavirus; Badnavirus gammavirgamusae.
OX NCBI_TaxID=1476909 {ECO:0000313|EMBL:AAW80648.1, ECO:0000313|Proteomes:UP000202191};
RN [1] {ECO:0000313|EMBL:AAW80648.1, ECO:0000313|Proteomes:UP000202191}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15785970; DOI=10.1007/s00705-004-0471-z;
RA Geering A.D., Pooggin M.M., Olszewski N.E., Lockhart B.E., Thomas J.E.;
RT "Characterisation of Banana streak Mysore virus and evidence that its DNA
RT is integrated in the B genome of cultivated Musa.";
RL Arch. Virol. 150:787-796(2005).
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DR EMBL; AY805074; AAW80648.1; -; Genomic_DNA.
DR RefSeq; YP_224289.1; NC_006955.1.
DR MEROPS; A03.003; -.
DR GeneID; 5141814; -.
DR KEGG; vg:5141814; -.
DR Proteomes; UP000202191; Genome.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR018061; Retropepsins.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR InterPro; IPR010666; Znf_GRF.
DR PANTHER; PTHR33064; POL PROTEIN; 1.
DR PANTHER; PTHR33064:SF36; RT_RNASEH_2 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00077; RVP; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF00098; zf-CCHC; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR PROSITE; PS50878; RT_POL; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
DR PROSITE; PS51999; ZF_GRF; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000202191};
KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00047}.
FT DOMAIN 762..778
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 1308..1490
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 1772..1810
FT /note="GRF-type"
FT /evidence="ECO:0000259|PROSITE:PS51999"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 937..1020
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1869 AA; 214956 MW; 3D0A6B939A87DAE9 CRC64;
MTTRRSSLPT VTETMGPSTS GRDGTPLIED QIRDYRASAR RRYEAQRVAR NIGNVGRRLI
GRQTREDTLA LLMDPEVELQ RSMRERARTV PAEVLYMSRR DDVHHRVYHF RSEERMMVSD
ADQQDRTFIS EESFERLQQA GLTYIHLGVL QVRFQILHRT FAGTMALLVF RDTRWTADDR
SIISAMEVDL AEGNQLIYVI PNIMMTIGDF YRHIQISIRT RGYDSWEGGE ANLLITRSVT
ARLSNTSNVG FAYRIDRVAE YLRTKGVRAI DATKHDARRF QHGEWNLRPS TAVVPVQPTS
ITSAVNYDRS ISLRFGDYQA ASSSRPPVYN KNDDEVDSDE ETFQINMVLL GDDMDYPMFR
ELEKLYITSE SMVGEDDEEE KSEDLDDEEA HADFQKFLNY SDEVNTIQDF LNQYDADISE
DEANYDVGVL EEYPELLKLE NNLAEIPILS EVTSQYRPAD IDMAGPTGYA PATSQQGLLG
STAPDRLGKG SFKWKSPTEY FNLPSAQQQA GAMFVMPANF DPKVFERWES ITLNHMADKV
FSTAEDKLIY LENLLGEAEK IMFQSWRMTY ANEYEEMKGQ ALGNNGTQNL LSQIRRIFYL
EDPKTGTTVS QDAAYKAIKS LVCHEMTGTA IKRYMADYWT LAAKTGRIWQ GPELSDEFFT
KLPSGLGDRV AKAFKEKYPG NTVGVPARIT FTQLYLEELC REAAYQRSLK NLDFCREFPI
PGYYKKPGRK FGVRKSTSYK GKPHKTHIKI DKRKYLRNKK CKCYACGEEG HYASECRNPR
KLMERVSVLQ DLELGKDMEI VSVEENETEL SDIYSISEGE ESGPPKSEIM SLELFMLHEI
EDEPEAYLIG ATDTWRNQMK VSRKEYYCQH EWDHTTKVVE RCRACTYYIT SQPRIKCTKC
KIPICNLCTN YCYGIKMADE KEKEKEKEKE SDLLGLVNNC REIMAKYRTE KEVLLEELNN
ALKQAKEYKE KFEHLEGICE EQEAENKALA QENQDLKEKV EELKEENEIL KDQNTTMGQE
MVKIQEKQQE AEKFLRREIK RREQANTEKL ALMMNEVCTE REYEYQINAT TVQNNLYNIK
IGLEVDGEKK FLNAILDTGA ATCVVSQAKV SERFLEPSAM KVELRGVNGT SKVNKVLKEG
KIWIGNQYFR LPRTYALEIE LSGGIDMIIG TNFLRAMSGG VRIEGETVTF YKIVTTTDAP
KVPHQINLIE ELEMSEEEFI EVQISTSTEG YINKEIMDSK LFKELKDQGY IGEEPLKHWQ
KNMVKCKLEL KNPDITIQDK PLKHVTAKMR ETMRAHIDKL LQLKVIRPSS SRHRTTAMIV
ESGTEVDPKT GQEKRGKERL VFNFKRLNDN TEKDQYSLPG INTIISRIGN AKVYSKFDLK
SGFHQVAMDP ESIPWTAFLA NNELYEWLVM PFGLKNAPAI FQRKMDTCFK GTEAFIAVYI
DDILVFSETE QLHRDHLRKF LEISKANGLI LSPTKMKIGV KTIDFLGASI GNSKIKLQPH
IIKKIADFDD HRLKETKGLR AWLGILNYAR NYIPNLGKTL GPLYSKISPN GEKRMNAQDW
ALVTQVKRQV QNLPELELPP EKCKMVIETD GCMEGWGGVC KWTTVGKAQE KVCAYASGKF
TPIKSTIDAE VQAVINSLDK FKIYYLDKKE LLIRTDCEAI VRFYKSTAQN KPSRVRWLML
TDFISGTGLE IKFEHINGCE NILADSLSRL VQTLLQGWQH QHLNGILLAL EELYQKPNPE
VAKKIGQIIM KVLEKPAGIQ INMITEGPKL RCACGKDAEI AVSHTSRNPD RPFYKCQRNL
CHIWIWKDLV DDYFQNLTAW NRISEEHRRE MAREEGQNLE EEDYWENVFN EVFDHEEITE
FYPDGGDPG
//
