ID Q5F2D9_MOUSE Unreviewed; 406 AA.
AC Q5F2D9;
DT 15-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE RecName: Full=Beta-arrestin-2 {ECO:0000256|ARBA:ARBA00040110};
DE AltName: Full=Arrestin beta-2 {ECO:0000256|ARBA:ARBA00042805};
GN Name=Arrb2 {ECO:0000313|EMBL:CAM28186.1,
GN ECO:0000313|Ensembl:ENSMUSP00000082018.7, ECO:0000313|MGI:MGI:99474};
GN ORFNames=DN-491F10.4-006 {ECO:0000313|EMBL:CAM28186.1};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000082018.7, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000082018.7, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000082018.7,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|EMBL:CAM28186.1}
RP NUCLEOTIDE SEQUENCE.
RA Kerry G.;
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000082018.7}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000082018.7};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the arrestin family.
CC {ECO:0000256|ARBA:ARBA00005298}.
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DR EMBL; CR936841; CAM28186.1; -; Genomic_DNA.
DR IntAct; Q5F2D9; 1.
DR ProteomicsDB; 328897; -.
DR Antibodypedia; 23372; 422 antibodies from 37 providers.
DR Ensembl; ENSMUST00000084954.13; ENSMUSP00000082018.7; ENSMUSG00000060216.16.
DR AGR; MGI:99474; -.
DR MGI; MGI:99474; Arrb2.
DR VEuPathDB; HostDB:ENSMUSG00000060216; -.
DR GeneTree; ENSGT00950000182887; -.
DR ChiTaRS; Arrb2; mouse.
DR Proteomes; UP000000589; Chromosome 11.
DR Bgee; ENSMUSG00000060216; Expressed in granulocyte and 247 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.40.640; -; 1.
DR Gene3D; 2.60.40.840; -; 1.
DR InterPro; IPR000698; Arrestin.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR011021; Arrestin-like_N.
DR InterPro; IPR011022; Arrestin_C-like.
DR InterPro; IPR017864; Arrestin_CS.
DR InterPro; IPR014753; Arrestin_N.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR11792; ARRESTIN; 1.
DR PANTHER; PTHR11792:SF20; BETA-ARRESTIN-2; 1.
DR Pfam; PF02752; Arrestin_C; 1.
DR Pfam; PF00339; Arrestin_N; 1.
DR PRINTS; PR00309; ARRESTIN.
DR SMART; SM01017; Arrestin_C; 1.
DR SUPFAM; SSF81296; E set domains; 2.
DR PROSITE; PS00295; ARRESTINS; 1.
PE 1: Evidence at protein level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Proteomics identification {ECO:0007829|EPD:Q5F2D9,
KW ECO:0007829|MaxQB:Q5F2D9};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 180..335
FT /note="Arrestin C-terminal-like"
FT /evidence="ECO:0000259|SMART:SM01017"
SQ SEQUENCE 406 AA; 45726 MW; E56B4BD9B1F6FCF2 CRC64;
MGEKPGTRVF KKSSPNCKLT VYLGKRDFVD HLDKVDPVVF VTLTCAFRYG REDLDVLGLS
FRKDLFIATY QAFPPMPNPP RPPTRLQDRL LKKLGQHAHP FFFTIPQNLP CSVTLQPGPE
DTGKACGVDF EIRAFCAKSI EEKSHKRNSV RLIIRKVQFA PETPGPQPSA ETTRHFLMSD
RRSLHLEASL DKELYYHGEP LNVNVHVTNN SAKTVKKIRV SVRQYADICL FSTAQYKCPV
AQLEQDDQVS PSSTFCKVYT ITPLLSDNRE KRGLALDGQL KHEDTNLASS TIVKEGANKE
VLGILVSYRV KVKLVVSRGG DVSVELPFVL MHPKPHDHIT LPRPQSAPIH PPLLCPSAPR
ETDVPVDTNL IEFDTNYATD DDIVFEDFAR LRLKGMKDDD CDDQFC
//
