ID Q5FIL2_LACAC Unreviewed; 212 AA.
AC Q5FIL2;
DT 01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=DUF421 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=LBA1650 {ECO:0000313|EMBL:AAV43462.1};
OS Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=272621 {ECO:0000313|Proteomes:UP000006381};
RN [1] {ECO:0000313|EMBL:AAV43462.1, ECO:0000313|Proteomes:UP000006381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700396 / NCK56 / N2 / NCFM
RC {ECO:0000313|Proteomes:UP000006381};
RX PubMed=15671160; DOI=10.1073/pnas.0409188102;
RA Altermann E., Russell W.M., Azcarate-Peril M.A., Barrangou R., Buck B.L.,
RA McAuliffe O., Souther N., Dobson A., Duong T., Callanan M., Lick S.,
RA Hamrick A., Cano R., Klaenhammer T.R.;
RT "Complete genome sequence of the probiotic lactic acid bacterium
RT Lactobacillus acidophilus NCFM.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:3906-3912(2005).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the UPF0702 family.
CC {ECO:0000256|ARBA:ARBA00006448}.
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DR EMBL; CP000033; AAV43462.1; -; Genomic_DNA.
DR RefSeq; WP_003550051.1; NC_006814.3.
DR RefSeq; YP_194493.1; NC_006814.3.
DR AlphaFoldDB; Q5FIL2; -.
DR STRING; 272621.LBA1650; -.
DR GeneID; 56943216; -.
DR KEGG; lac:LBA1650; -.
DR PATRIC; fig|272621.13.peg.1570; -.
DR eggNOG; COG2323; Bacteria.
DR HOGENOM; CLU_077149_4_0_9; -.
DR OrthoDB; 9778331at2; -.
DR BioCyc; LACI272621:G1G49-1618-MONOMER; -.
DR Proteomes; UP000006381; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.30.240.20; bsu07140 like domains; 2.
DR InterPro; IPR007353; DUF421.
DR InterPro; IPR023090; UPF0702_alpha/beta_dom_sf.
DR InterPro; IPR048454; YetF_N.
DR PANTHER; PTHR34582; UPF0702 TRANSMEMBRANE PROTEIN YCAP; 1.
DR PANTHER; PTHR34582:SF6; UPF0702 TRANSMEMBRANE PROTEIN YCAP; 1.
DR Pfam; PF04239; DUF421; 1.
DR Pfam; PF20730; YetF_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006381};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..79
FT /note="YetF-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF20730"
FT DOMAIN 83..200
FT /note="YetF C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04239"
SQ SEQUENCE 212 AA; 23936 MW; 2F741CA06121820C CRC64;
MQLDYTQLFI KFALGILTLI IQINVFGKSN LAPTTALDQL QNYVLGGIIG GLIYNPSISI
LQFLLVLILW TLVVFILKFS RDHNNWVRGI VDGKPVQVIK NGKVLVGNCM KAGISANELM
FKLRSRGIYS VEKIKNCIFE QNGQLTIIEN DEDNIRFPII SDGQANIDVL ELIHKDETWL
EQEVKKAGYN SINDIFLGEY IDGKLHFTGY TN
//
