ID Q5FJG9_LACAC Unreviewed; 270 AA.
AC Q5FJG9;
DT 01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Hemolysin-like protein {ECO:0000313|EMBL:AAV43155.1};
GN OrderedLocusNames=LBA1328 {ECO:0000313|EMBL:AAV43155.1};
OS Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=272621 {ECO:0000313|Proteomes:UP000006381};
RN [1] {ECO:0000313|EMBL:AAV43155.1, ECO:0000313|Proteomes:UP000006381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700396 / NCK56 / N2 / NCFM
RC {ECO:0000313|Proteomes:UP000006381};
RX PubMed=15671160; DOI=10.1073/pnas.0409188102;
RA Altermann E., Russell W.M., Azcarate-Peril M.A., Barrangou R., Buck B.L.,
RA McAuliffe O., Souther N., Dobson A., Duong T., Callanan M., Lick S.,
RA Hamrick A., Cano R., Klaenhammer T.R.;
RT "Complete genome sequence of the probiotic lactic acid bacterium
RT Lactobacillus acidophilus NCFM.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:3906-3912(2005).
CC -!- SIMILARITY: Belongs to the TlyA family.
CC {ECO:0000256|ARBA:ARBA00029460}.
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DR EMBL; CP000033; AAV43155.1; -; Genomic_DNA.
DR RefSeq; WP_003547933.1; NC_006814.3.
DR RefSeq; YP_194186.1; NC_006814.3.
DR AlphaFoldDB; Q5FJG9; -.
DR STRING; 272621.LBA1328; -.
DR GeneID; 56942912; -.
DR KEGG; lac:LBA1328; -.
DR PATRIC; fig|272621.13.peg.1256; -.
DR eggNOG; COG1189; Bacteria.
DR HOGENOM; CLU_058015_3_0_9; -.
DR OrthoDB; 9784736at2; -.
DR BioCyc; LACI272621:G1G49-1305-MONOMER; -.
DR Proteomes; UP000006381; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004538; Hemolysin_A/TlyA.
DR InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR047048; TlyA.
DR NCBIfam; TIGR00478; tly; 1.
DR PANTHER; PTHR32319; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR32319:SF0; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR Pfam; PF01728; FtsJ; 1.
DR PIRSF; PIRSF005578; TlyA; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006381};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182}.
FT DOMAIN 4..70
FT /note="RNA-binding S4"
FT /evidence="ECO:0000259|SMART:SM00363"
SQ SEQUENCE 270 AA; 30230 MW; 88F3260C22BFD2BD CRC64;
MAKQRADVLL AEQGIFHSRS AAQRAIMAGL VSDHNHQRID KSGTKFPEDE KFYVKDDGKK
YVSRGGFKLE KALKVFNINL KDKICLDIGA STGGFTDVAL QNGAKMVYAL DVGYNQLAWQ
LRDDPRVVVM EKQNFRYSKP EDFDQGLPDF AMTDVSFISL DLIMPPMYAI LKDQCDAVCL
IKPQFEAGPE NVGKHGIVHD HEVHKQVIEH TMQEALKIGF NVLGVDYSPI KGGKGNIEFL
IHLQKDEANG SRNLWQGKPE EIVERAVNGL
//
