ID Q5FLD0_LACAC Unreviewed; 434 AA.
AC Q5FLD0;
DT 01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Amino acid permease {ECO:0000313|EMBL:AAV42494.1};
GN OrderedLocusNames=LBA0615 {ECO:0000313|EMBL:AAV42494.1};
OS Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=272621 {ECO:0000313|Proteomes:UP000006381};
RN [1] {ECO:0000313|EMBL:AAV42494.1, ECO:0000313|Proteomes:UP000006381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700396 / NCK56 / N2 / NCFM
RC {ECO:0000313|Proteomes:UP000006381};
RX PubMed=15671160; DOI=10.1073/pnas.0409188102;
RA Altermann E., Russell W.M., Azcarate-Peril M.A., Barrangou R., Buck B.L.,
RA McAuliffe O., Souther N., Dobson A., Duong T., Callanan M., Lick S.,
RA Hamrick A., Cano R., Klaenhammer T.R.;
RT "Complete genome sequence of the probiotic lactic acid bacterium
RT Lactobacillus acidophilus NCFM.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:3906-3912(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000033; AAV42494.1; -; Genomic_DNA.
DR RefSeq; WP_011254206.1; NC_006814.3.
DR RefSeq; YP_193525.1; NC_006814.3.
DR AlphaFoldDB; Q5FLD0; -.
DR STRING; 272621.LBA0615; -.
DR GeneID; 56942247; -.
DR KEGG; lac:LBA0615; -.
DR PATRIC; fig|272621.13.peg.588; -.
DR eggNOG; COG0531; Bacteria.
DR HOGENOM; CLU_007946_3_4_9; -.
DR OrthoDB; 3181223at2; -.
DR BioCyc; LACI272621:G1G49-639-MONOMER; -.
DR Proteomes; UP000006381; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR PANTHER; PTHR11785; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR11785:SF512; SOBREMESA, ISOFORM B; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006381};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 41..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 434 AA; 47121 MW; 6CB0ED25A3B92D00 CRC64;
MKRQISFGQA LATVVGSVIG AGVFFKIGTI TAQTGSSSMT LLVWVLAGII SIASGLTISE
IAASLKINGA IKYLDYTYGR VWGFLFGWAQ MIVYFPAQIG ALSSIFGVQF VSLFGIEAKY
SNLIAVILVL FLLSINLIGT KFSSKMQSVI TILKIIPIIL IIVLGLFNQN KVSAPIFPVT
VGSSKDLIGS LSQGLLSALF AFEGWIVVTN LANEVKNPEN DLSRAIISGL SIVTLIYVLI
NYTFLTVLPI NQLVNNDNAA FEASMKLFGQ FGGKLITIGI LISVYGAANA FMLTGMRTPY
ILAQDRLLPF SNKIGKANIH TGVPVTGALI VDAIAIIMII LGNFTVLTDM LVFVMWTFNT
MLSIAVVILR KREPELRRPF KVPWYPIIPI ISVLGGLFIV ISTIINQFLL SLIGIGLTLI
GLPIYYHMQK KNQN
//
