ID Q5FM41_LACAC Unreviewed; 146 AA.
AC Q5FM41;
DT 01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=Pga mutase {ECO:0000313|EMBL:AAV42233.1};
DE EC=5.4.2.1 {ECO:0000313|EMBL:AAV42233.1};
GN OrderedLocusNames=LBA0341 {ECO:0000313|EMBL:AAV42233.1};
OS Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=272621 {ECO:0000313|Proteomes:UP000006381};
RN [1] {ECO:0000313|EMBL:AAV42233.1, ECO:0000313|Proteomes:UP000006381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700396 / NCK56 / N2 / NCFM
RC {ECO:0000313|Proteomes:UP000006381};
RX PubMed=15671160; DOI=10.1073/pnas.0409188102;
RA Altermann E., Russell W.M., Azcarate-Peril M.A., Barrangou R., Buck B.L.,
RA McAuliffe O., Souther N., Dobson A., Duong T., Callanan M., Lick S.,
RA Hamrick A., Cano R., Klaenhammer T.R.;
RT "Complete genome sequence of the probiotic lactic acid bacterium
RT Lactobacillus acidophilus NCFM.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:3906-3912(2005).
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DR EMBL; CP000033; AAV42233.1; -; Genomic_DNA.
DR RefSeq; YP_193264.1; NC_006814.3.
DR AlphaFoldDB; Q5FM41; -.
DR STRING; 272621.LBA0341; -.
DR KEGG; lac:LBA0341; -.
DR PATRIC; fig|272621.13.peg.327; -.
DR eggNOG; COG0588; Bacteria.
DR HOGENOM; CLU_2054534_0_0_9; -.
DR OrthoDB; 9781415at2; -.
DR BioCyc; LACI272621:G1G49-335-MONOMER; -.
DR Proteomes; UP000006381; Chromosome.
DR GO; GO:0016868; F:intramolecular phosphotransferase activity; IEA:InterPro.
DR GO; GO:0006096; P:glycolytic process; IEA:InterPro.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR005952; Phosphogly_mut1.
DR NCBIfam; TIGR01258; pgm_1; 1.
DR PANTHER; PTHR11931; PHOSPHOGLYCERATE MUTASE; 1.
DR PANTHER; PTHR11931:SF0; PHOSPHOGLYCERATE MUTASE; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
PE 4: Predicted;
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:AAV42233.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006381}.
FT BINDING 9..12
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
FT BINDING 20
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
FT BINDING 36..37
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
FT SITE 99
FT /note="Transition state stabilizer"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-3"
SQ SEQUENCE 146 AA; 17009 MW; CCC63DDB273AC0C2 CRC64;
MTKTWRLNER HYGALRGLNK DVSRKVFGVE QVLLWRRGFN SIPPAQGSPV IDRRYKLCDQ
HLMPRAESLH QTQNRLMPYY YDHIAPKLLN GEDQLIVAHG SSLRALIKKL ENINDHDIVN
LEVPNAEPIV YTMDDQLNII NKKILR
//
