ID Q5FMU7_LACAC Unreviewed; 530 AA.
AC Q5FMU7;
DT 01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 119.
DE SubName: Full=ABC transporter bacteriocin {ECO:0000313|EMBL:AAV41977.1};
GN OrderedLocusNames=LBA0074 {ECO:0000313|EMBL:AAV41977.1};
OS Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=272621 {ECO:0000313|Proteomes:UP000006381};
RN [1] {ECO:0000313|EMBL:AAV41977.1, ECO:0000313|Proteomes:UP000006381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700396 / NCK56 / N2 / NCFM
RC {ECO:0000313|Proteomes:UP000006381};
RX PubMed=15671160; DOI=10.1073/pnas.0409188102;
RA Altermann E., Russell W.M., Azcarate-Peril M.A., Barrangou R., Buck B.L.,
RA McAuliffe O., Souther N., Dobson A., Duong T., Callanan M., Lick S.,
RA Hamrick A., Cano R., Klaenhammer T.R.;
RT "Complete genome sequence of the probiotic lactic acid bacterium
RT Lactobacillus acidophilus NCFM.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:3906-3912(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000033; AAV41977.1; -; Genomic_DNA.
DR RefSeq; WP_003548575.1; NC_006814.3.
DR RefSeq; YP_193008.1; NC_006814.3.
DR AlphaFoldDB; Q5FMU7; -.
DR STRING; 272621.LBA0074; -.
DR GeneID; 56941690; -.
DR KEGG; lac:LBA0074; -.
DR PATRIC; fig|272621.13.peg.73; -.
DR eggNOG; COG1132; Bacteria.
DR HOGENOM; CLU_000604_84_3_9; -.
DR OrthoDB; 2321410at2; -.
DR BioCyc; LACI272621:G1G49-74-MONOMER; -.
DR Proteomes; UP000006381; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03228; ABCC_MRP_Like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221:SF658; ABC TRANSPORTER B FAMILY MEMBER 29, CHLOROPLASTIC; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006381};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..291
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 321..529
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 530 AA; 59870 MW; 9E45D20CAF7DD72B CRC64;
MNLKDLFKTN KLRFIAICLL VAIEILCATS VTYFMTPAFN YIKQNKLNIF LIFIIFSAAL
QLLDTILQSI NMVLYNQQVQ DYIHNIRNNI SRYFFHKSEE KVAEIQNDLD TNMQELTSKY
TTPLLVLGRR ILTILFSIGV LFTFNWSLVV LTLLLSFIGL YLPKIFEKVT SSATFEVTKK
NEQLLNTIGK WAQGLSELRR YASLKSYKKA IQNSTSELKN ATIKDCYWGN WATAATSFVS
LLGIALLLFL SIYLYATGQI VFGAVITSGI FANQIMNSVT YLADSINQIK SSKKLRQEIS
KLQQPVEFTV PDNSAQNIAH IEVSDLQVSF KNGENISYPH IQINKGEKVL LSGDSGVGKT
TLFKVLLGQI KPKRGQIIYK NEQGQSFMPD LERIGYIAQD NTLFPDTIEN NITMFDTKLT
GKVTEAIKKV KLDKDIKKFP AGVKTMVDLD HGNISGGQKQ KIVLARADIH NSDLLLIDEG
TSAIDSKATK EILKEILKSD RTIIMIAHNL SQEMIAMFDY KIDLRKMEVN
//
