ID Q5GSG7_WOLTR Unreviewed; 544 AA.
AC Q5GSG7;
DT 01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=Predicted hydrolase of the metallo-beta-lactamase superfamily {ECO:0000313|EMBL:AAW71057.1};
GN OrderedLocusNames=Wbm0469 {ECO:0000313|EMBL:AAW71057.1};
OS Wolbachia sp. subsp. Brugia malayi (strain TRS).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Wolbachieae; Wolbachia.
OX NCBI_TaxID=292805 {ECO:0000313|EMBL:AAW71057.1, ECO:0000313|Proteomes:UP000000534};
RN [1] {ECO:0000313|EMBL:AAW71057.1, ECO:0000313|Proteomes:UP000000534}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TRS {ECO:0000313|Proteomes:UP000000534};
RX PubMed=15780005; DOI=10.1371/journal.pbio.0030121;
RA Foster J., Ganatra M., Kamal I., Ware J., Makarova K., Ivanova N.,
RA Bhattacharyya A., Kapatral V., Kumar S., Posfai J., Vincze T., Ingram J.,
RA Moran L., Lapidus A., Omelchenko M., Kyrpides N., Ghedin E., Wang S.,
RA Goltsman E., Joukov V., Ostrovskaya O., Tsukerman K., Mazur M., Comb D.,
RA Koonin E., Slatko B.;
RT "The Wolbachia genome of Brugia malayi: endosymbiont evolution within a
RT human pathogenic nematode.";
RL PLoS Biol. 3:599-614(2005).
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DR EMBL; AE017321; AAW71057.1; -; Genomic_DNA.
DR RefSeq; WP_011256667.1; NC_006833.1.
DR AlphaFoldDB; Q5GSG7; -.
DR STRING; 292805.Wbm0469; -.
DR KEGG; wbm:Wbm0469; -.
DR eggNOG; COG0595; Bacteria.
DR HOGENOM; CLU_008727_3_3_5; -.
DR Proteomes; UP000000534; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR CDD; cd07714; RNaseJ_MBL-fold; 1.
DR Gene3D; 3.10.20.580; -; 1.
DR Gene3D; 3.40.50.10710; Metallo-hydrolase/oxidoreductase; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR InterPro; IPR042173; RNase_J_2.
DR InterPro; IPR041636; RNase_J_C.
DR PANTHER; PTHR43694; RIBONUCLEASE J; 1.
DR PANTHER; PTHR43694:SF1; RIBONUCLEASE J; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF07521; RMMBL; 1.
DR Pfam; PF17770; RNase_J_C; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AAW71057.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000000534};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 20..216
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 544 AA; 60528 MW; 1BA879D711BD45FF CRC64;
MNINKNEFLF LPLGGVGRIG MNVNLYHYRG KWIMIDLGIG FADETMPGIE LLIADVSFIA
QRKKDLLGII ITHAHEDHCG AVPYLWKELQ CPIYTTKFTA NFLKEKLKEF RLEGMVSVKE
VDINGSINLS PFTVEFINVT HSIPEAHSIL VSTDVGSALH TGDWKFDQKP IVGLTSNISR
LKEIGDKGNL LAAICDSTNV LGKHNPESES EIYNNIYNII RRSKKLVAVS LFASNVARIE
TIGQVAKVLG RKVVLLGRSL WRIVRVAQNS GYLTDSVEFC EVKDVADLPR EKLLLICTGC
QGEPMAAISK LANKSHHAFK MQQGDTVIFS SKIIPGNETR AHVIFNAFIE MGVEIVTEKT
ECVHASGHPV KAELREMYSL IKPKMSIPVH GEYIHTHAHV KFAKECGVEK AIMIAPGDIV
NLENGKKVDS INVNYFGVDG ILLRHPGSNV IRMRKKMRDA GTIVVTAIVN KRNKLLAKPK
VFAPGVLEAV EDAAIIQRII KAVESAFNLQ STKKVRNKIE SLIFSILKEY LLKRPIIEVQ
IEQV
//
