ID Q5H3U9_XANOR Unreviewed; 836 AA.
AC Q5H3U9;
DT 01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=NADP-dependent malic enzyme {ECO:0000313|EMBL:AAW74372.1};
GN Name=maeB {ECO:0000313|EMBL:AAW74372.1};
GN OrderedLocusNames=XOO1118 {ECO:0000313|EMBL:AAW74372.1};
OS Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xanthomonas.
OX NCBI_TaxID=291331 {ECO:0000313|EMBL:AAW74372.1, ECO:0000313|Proteomes:UP000006735};
RN [1] {ECO:0000313|EMBL:AAW74372.1, ECO:0000313|Proteomes:UP000006735}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KACC10331 / KXO85 {ECO:0000313|Proteomes:UP000006735};
RX PubMed=15673718; DOI=10.1093/nar/gki206;
RA Lee B.M., Park Y.J., Park D.S., Kang H.W., Kim J.G., Song E.S., Park I.C.,
RA Yoon U.H., Hahn J.H., Koo B.S., Lee G.B., Kim H., Park H.S., Yoon K.O.,
RA Kim J.H., Jung C.H., Koh N.H., Seo J.S., Go S.J.;
RT "The genome sequence of Xanthomonas oryzae pathovar oryzae KACC10331, the
RT bacterial blight pathogen of rice.";
RL Nucleic Acids Res. 33:577-586(2005).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; AE013598; AAW74372.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5H3U9; -.
DR STRING; 291331.XOO1118; -.
DR KEGG; xoo:XOO1118; -.
DR HOGENOM; CLU_012366_0_0_6; -.
DR Proteomes; UP000006735; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR GO; GO:0004470; F:malic enzyme activity; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05311; NAD_bind_2_malic_enz; 1.
DR Gene3D; 3.40.50.10950; -; 1.
DR Gene3D; 3.40.50.10750; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR Gene3D; 3.40.50.10380; Malic enzyme, N-terminal domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR012301; Malic_N_dom.
DR InterPro; IPR037062; Malic_N_dom_sf.
DR InterPro; IPR012302; Malic_NAD-bd.
DR InterPro; IPR045213; Malic_NAD-bd_bact_type.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR042113; P_AcTrfase_dom1.
DR InterPro; IPR042112; P_AcTrfase_dom2.
DR InterPro; IPR002505; PTA_PTB.
DR PANTHER; PTHR43237; NADP-DEPENDENT MALIC ENZYME; 1.
DR PANTHER; PTHR43237:SF4; NADP-DEPENDENT MALIC ENZYME; 1.
DR Pfam; PF00390; malic; 1.
DR Pfam; PF03949; Malic_M; 1.
DR Pfam; PF01515; PTA_PTB; 1.
DR SMART; SM01274; malic; 1.
DR SMART; SM00919; Malic_M; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006735}.
FT DOMAIN 86..219
FT /note="Malic enzyme N-terminal"
FT /evidence="ECO:0000259|SMART:SM01274"
FT DOMAIN 231..466
FT /note="Malic enzyme NAD-binding"
FT /evidence="ECO:0000259|SMART:SM00919"
FT REGION 48..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 836 AA; 90645 MW; 756575C820A0072F CRC64;
MMLPAALSSV GIAGGMQGRF RVEPHSAPRT PRCSMRSPCR ADSCATGPCS GRRVEFSSPA
PSRHTQPMST DDFKQAALDY HRQQPAGKIK VTATKPMLTQ RDLSLAYSPG VAFACEAIVD
DATQASELTA RGNLVAVITN GTAVLGLGNI GPLASKPVME GKGVLFQKFA GIDVFDIEIS
ENDPDKLVDI IASLEPTFGG INLEDIKAPE CFIVERKLRE RMNIPVFHDD QHGTAIIVGA
AVLNALVVTG KKIEEVKLAT TGMGAAGISC VNMLVSLGLK PENILALDRD GVIHTGRTDL
DPDKQRYARD TDKRTLAEIV EGADIFLGLS AAGILKPEMV ASMARQPVIF ALANPNPEIT
PEAAKAVRPD CIIGTGRSDY PNQINNVLCF PYLFRGALDV GATGINEEMK IACVKAIAAM
ARREASDLGA AYGGETPSFG PEYLIPRPLD PRLLVELSSA VAQAAMDSGV ATRPITDMEA
YRDKLGQFVY RTSLMMKPVY DRARADKQRV VYAEGEEEVV LRAVQNVVDE GLAFPILIGR
PDVIEARIER MGLRLTAGVD FEITNILDDP RFNDYWQYYH ALTERRGVTV TAAKELMRSR
PTLIAAVMVA RGEADAMLSG VVGRFHKKLG YARSVIPLEP RVSSTSAMTG VINQLGVFFF
LDTHVQEDPT VEQVVEATLQ AAYRLKLFGI EPNIALLSHS NFGSHDSRDA LKMRQVREAL
LKRKPELNID GEMQGDTAWD EALRKQIMPN STLKGRANLF VLPNLEAANI AYNLVRVFTD
GVAIGPILMG ISKPVHILTT SATSRRVMNM TAIAAVDAQI RKLLEAEKGG ADKSND
//
