ID V1R94_RAT Reviewed; 326 AA.
AC Q5J3M4;
DT 13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 24-JAN-2024, entry version 105.
DE RecName: Full=Vomeronasal type-1 receptor 94;
DE AltName: Full=Vomeronasal type-1 receptor A13;
GN Name=Vom1r94; Synonyms=V1ra13;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1] {ECO:0000312|EMBL:AAR87953.1}
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Capello L., Rodriguez I.;
RT "Rat vomeronasal receptors.";
RL Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Putative pheromone receptor implicated in the regulation of
CC social as well as reproductive behavior.
CC {ECO:0000250|UniProtKB:Q8VIC6}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AY510286; AAR87953.1; -; mRNA.
DR AlphaFoldDB; Q5J3M4; -.
DR SMR; Q5J3M4; -.
DR BioGRID; 268880; 1.
DR IntAct; Q5J3M4; 1.
DR MINT; Q5J3M4; -.
DR GlyCosmos; Q5J3M4; 1 site, No reported glycans.
DR GlyGen; Q5J3M4; 1 site.
DR PaxDb; 10116-ENSRNOP00000047560; -.
DR UCSC; RGD:1359098; rat.
DR AGR; RGD:1359098; -.
DR RGD; 1359098; Vom1r94.
DR VEuPathDB; HostDB:ENSRNOG00000031140; -.
DR eggNOG; ENOG502SNRJ; Eukaryota.
DR HOGENOM; CLU_058641_0_0_1; -.
DR InParanoid; Q5J3M4; -.
DR OrthoDB; 4113734at2759; -.
DR PhylomeDB; Q5J3M4; -.
DR PRO; PR:Q5J3M4; -.
DR Proteomes; UP000002494; Chromosome 4.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016503; F:pheromone receptor activity; IEA:InterPro.
DR GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR GO; GO:0007606; P:sensory perception of chemical stimulus; IEA:UniProt.
DR CDD; cd13949; 7tm_V1R_pheromone; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR004072; Vmron_rcpt_1.
DR PANTHER; PTHR24062; VOMERONASAL TYPE-1 RECEPTOR; 1.
DR PANTHER; PTHR24062:SF167; VOMERONASAL TYPE-1 RECEPTOR 42-RELATED; 1.
DR Pfam; PF03402; V1R; 1.
DR PRINTS; PR01534; VOMERONASL1R.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Pheromone response; Receptor; Reference proteome; Transducer;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..326
FT /note="Vomeronasal type-1 receptor 94"
FT /id="PRO_0000239969"
FT TOPO_DOM 1..32
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 33..53
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 54..65
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 66..86
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 87..110
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 111..130
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 131..150
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 172..203
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 204..224
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 225..254
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 255..275
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 276..285
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 286..306
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 307..326
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 175
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 101..188
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 326 AA; 37166 MW; E3EAD56ABF652A90 CRC64;
MSEILLFSPQ PLFSYTMNKY SRLYTNSNIR NTFFSEIGIG IAANSLLLLF HIFKFIRGQR
SRLTDLPIGL LSLIHLLKLL MIAFIATDIF ISWRGWDDII CKFLVYLYRS FRGLSLCTTC
MLSVLQAITL SPRSSCLAKF KHKSPHHVSC AILSLSVLYM FISSHLLVSL IATPNLTTNV
FMYVSESCSI LPMSYLMQSM FSTLLAIRDV FLISLMVLST CYMVALLCRH RKQTRHLQGT
SLSPKASPEK KATHSILMLM SFFVLMSILD SIVSCSRTMF LYDPTSYAIQ IFVSHIYATV
SPFVFMSNEK HIVNFLRSLC KRVINV
//
