ID Q5JES1_THEKO Unreviewed; 561 AA.
AC Q5JES1;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Aminopeptidase, family M28, containing PA domain {ECO:0000313|EMBL:BAD86101.1};
GN OrderedLocusNames=TK1912 {ECO:0000313|EMBL:BAD86101.1};
OS Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS (Pyrococcus kodakaraensis (strain KOD1)).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=69014 {ECO:0000313|EMBL:BAD86101.1, ECO:0000313|Proteomes:UP000000536};
RN [1] {ECO:0000313|EMBL:BAD86101.1, ECO:0000313|Proteomes:UP000000536}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-918 / JCM 12380 / KOD1
RC {ECO:0000313|Proteomes:UP000000536};
RX PubMed=15710748; DOI=10.1101/gr.3003105;
RA Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL Genome Res. 15:352-363(2005).
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DR EMBL; AP006878; BAD86101.1; -; Genomic_DNA.
DR RefSeq; WP_011250863.1; NC_006624.1.
DR AlphaFoldDB; Q5JES1; -.
DR STRING; 69014.TK1912; -.
DR EnsemblBacteria; BAD86101; BAD86101; TK1912.
DR GeneID; 78448445; -.
DR KEGG; tko:TK1912; -.
DR PATRIC; fig|69014.16.peg.1869; -.
DR eggNOG; arCOG02959; Archaea.
DR HOGENOM; CLU_035477_0_0_2; -.
DR InParanoid; Q5JES1; -.
DR OrthoDB; 18376at2157; -.
DR PhylomeDB; Q5JES1; -.
DR Proteomes; UP000000536; Chromosome.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IBA:GO_Central.
DR CDD; cd05643; M28_like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR045175; M28_fam.
DR InterPro; IPR007484; Peptidase_M28.
DR PANTHER; PTHR12147:SF26; ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1; 1.
DR PANTHER; PTHR12147; METALLOPEPTIDASE M28 FAMILY MEMBER; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 4: Predicted;
KW Aminopeptidase {ECO:0000313|EMBL:BAD86101.1};
KW Hydrolase {ECO:0000313|EMBL:BAD86101.1};
KW Protease {ECO:0000313|EMBL:BAD86101.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000536}.
FT DOMAIN 225..408
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
SQ SEQUENCE 561 AA; 62852 MW; F97FE43C6B034E3B CRC64;
MERFLRDSAE FSSDNVLNWI AGISHFHRIQ GSKGLVEAAE YVLEELSRMG LEAKLLKDKY
DGKRWHLTLP SPIAWEVIDG RLEVPGRTLT TAESPLLVMA HSPSGEVDGE VLPILRQEDW
ERAEGKVVLV GKDWRDAYRR ANEVGASGFI AYREGTGEFY PYIGLFLTKE DLNWAQIPAF
AVPEAVAKGL IRRALSGGVE VRGTAETEIK SSETLPMVYA EVGEPPYLLF TAHICHPKPG
ANDNASGNAM LLELARVLSK RENGRFGYAF LWVPEYHGSQ AFIERAGVEE YYAGINLDMV
AGSPDRSEST LMFVRTPFSR FSVVSGALEV AIELSNSRGK SFSGSRLPVM PFRAYPYEMG
SDHDIFNFFG VPSVMPITWP DRFYHSSGDT IDKVSRETVA IVERAVLSAA LFLSEEEKRR
IEQFARGYAR KVLGEIGMRL EPKESEKLVK AGLARDAEFL GLELNLEVET KAKPWLEWKE
RGLISERLIR SRAPGLAEDF KKLTEERATV THLHELIMLG ELLSEGNAYR AIEEEYGSIE
REKLKRLVEI LEEVGVVALS S
//
