ID   Q5JH24_THEKO            Unreviewed;       648 AA.
AC   Q5JH24;
DT   15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2005, sequence version 1.
DT   27-MAR-2024, entry version 98.
DE   SubName: Full=Cleavage and polyadenylation specficity factor subunit homolog {ECO:0000313|EMBL:BAD85617.1};
GN   OrderedLocusNames=TK1428 {ECO:0000313|EMBL:BAD85617.1};
OS   Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS   (Pyrococcus kodakaraensis (strain KOD1)).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014 {ECO:0000313|EMBL:BAD85617.1, ECO:0000313|Proteomes:UP000000536};
RN   [1] {ECO:0000313|EMBL:BAD85617.1, ECO:0000313|Proteomes:UP000000536}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-918 / JCM 12380 / KOD1
RC   {ECO:0000313|Proteomes:UP000000536};
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT   kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL   Genome Res. 15:352-363(2005).
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DR   EMBL; AP006878; BAD85617.1; -; Genomic_DNA.
DR   RefSeq; WP_011250379.1; NC_006624.1.
DR   AlphaFoldDB; Q5JH24; -.
DR   SMR; Q5JH24; -.
DR   STRING; 69014.TK1428; -.
DR   EnsemblBacteria; BAD85617; BAD85617; TK1428.
DR   GeneID; 78447952; -.
DR   KEGG; tko:TK1428; -.
DR   PATRIC; fig|69014.16.peg.1389; -.
DR   eggNOG; arCOG00543; Archaea.
DR   HOGENOM; CLU_009673_5_1_2; -.
DR   InParanoid; Q5JH24; -.
DR   OrthoDB; 7155at2157; -.
DR   PhylomeDB; Q5JH24; -.
DR   Proteomes; UP000000536; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0004521; F:RNA endonuclease activity; IBA:GO_Central.
DR   CDD; cd22532; KH-II_CPSF_arch_rpt1; 1.
DR   CDD; cd02410; KH-II_CPSF_arch_rpt2; 1.
DR   CDD; cd16295; TTHA0252-CPSF-like_MBL-fold; 1.
DR   Gene3D; 3.30.300.20; -; 1.
DR   Gene3D; 3.30.300.230; -; 1.
DR   Gene3D; 3.40.50.10890; -; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR019975; aCPSF1.
DR   InterPro; IPR022712; Beta_Casp.
DR   InterPro; IPR033769; KH_arc.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR015946; KH_dom-like_a/b.
DR   InterPro; IPR009019; KH_sf_prok-type.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR011108; RMMBL.
DR   NCBIfam; TIGR03675; arCOG00543; 1.
DR   PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR   PANTHER; PTHR11203:SF37; INTEGRATOR COMPLEX SUBUNIT 11; 1.
DR   Pfam; PF10996; Beta-Casp; 1.
DR   Pfam; PF17214; KH_7; 1.
DR   Pfam; PF16661; Lactamase_B_6; 1.
DR   Pfam; PF07521; RMMBL; 1.
DR   SMART; SM01027; Beta-Casp; 1.
DR   SMART; SM00322; KH; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR   SUPFAM; SSF54814; Prokaryotic type KH domain (KH-domain type II); 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000536}.
FT   DOMAIN          102..169
FT                   /note="K Homology"
FT                   /evidence="ECO:0000259|SMART:SM00322"
FT   DOMAIN          198..428
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
FT   DOMAIN          433..557
FT                   /note="Beta-Casp"
FT                   /evidence="ECO:0000259|SMART:SM01027"
SQ   SEQUENCE   648 AA;  73504 MW;  B17CBF8BBE076372 CRC64;
     MIRRETFVDD ILKEIREIIV QMVPREAGIT DVEFEGPELV IYVKNPEAMM KDGELIKNLA
     KVLKKRISVR PDPDILLPPE KAEELIKQLV PPEAEITNIS FDPSVGEVLI EARKPGLVIG
     KNGETLRLIT QKVHWAPRVV RTPPIQSQTI YSIRSILQTE SKDRRKFLRQ VGRNIYRKSE
     YKSRWIRITG LGGFREVGRS ALLVQTDESY VLVDFGVNIA ALKDPTKAYP HFDAPEFRYV
     LDEGLLDAII ITHAHLDHSG MLPYLFRYKL FDGPIYTTPP TRDLMTLLQQ DFIEIQHMNG
     VEPLYRPKDI KEVIKHTITL DYGEVRDIAP DIRLTLHNAG HILGSSIVHL HIGNGLHNIA
     ITGDFKFIPT RLFEPAVSRF PRLETLVMES TYGGSNDYQM PREEAEKRLI EVIHQTLKRG
     GKVLIPAMAV GRAQEIMMVL EEYARVGGIE VPIYLDGMIW EATAIHTAYP EYLSKHIREQ
     IFHEGYNPFL NPIFKSVANS RERQDIIDSG EPAIIIATSG MLVGGPSVEY FKQLAPDPKN
     SIIFVSYQAE GTLGRQVQRG LREIPIVGED GRTEVINVNM EVHTIDGFSG HADRRELMSY
     VARVRPRPER IITVHGEAHK CLDLSSSIHK KFGISTRAPN NLDAIRLK
//