ID Q5K7G3_CRYNJ Unreviewed; 564 AA.
AC Q5K7G3;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 2.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=Trehalose transport-related protein, putative {ECO:0000313|EMBL:AAW46732.2};
GN OrderedLocusNames=CNM02540 {ECO:0000313|EMBL:AAW46732.2};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW46732.2, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW46732.2, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
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DR EMBL; AE017353; AAW46732.2; -; Genomic_DNA.
DR RefSeq; XP_568249.1; XM_568249.1.
DR AlphaFoldDB; Q5K7G3; -.
DR PaxDb; 214684-Q5K7G3; -.
DR EnsemblFungi; AAW46732; AAW46732; CNM02540.
DR VEuPathDB; FungiDB:CNM02540; -.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_001265_11_0_1; -.
DR InParanoid; Q5K7G3; -.
DR OrthoDB; 1477450at2759; -.
DR Proteomes; UP000002149; Chromosome 13.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR48022; PLASTIDIC GLUCOSE TRANSPORTER 4; 1.
DR PANTHER; PTHR48022:SF33; SUGAR PERMEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G12040)-RELATED; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002149};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 135..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..443
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 58..511
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 542..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 564 AA; 62258 MW; A2508087EA9D56CD CRC64;
MTLNTVTPVI VEEEKMDVEH VEEAKVDNEF DPNLVIKSPF EDLSFFVTLK TFKKATFLAL
LAAFSAAADG YQIAMTGSII ANKGFIQTYG TAYNSAGELI LDANVLAAWG GVQSAGQGLG
MLSMHFIADK FGRKWAFYGL WLALVLGVTC ETVGRHWQIW LVAKLASGYG VGSVQFLTGT
YITEIVPSRT RGFILIFYSI WYAIGQLFAS AALKVLADQQ PYNYLDLIYT EWAMIGIMIM
AYLYLPESPW WYANHNKDDR GRAVVERLNG GIEGYDVDFH YSLIKKTVDN EKAQKTATLG
ADRGFWKGLW DCREVFTGAN GFRTLVAFYP AAIQQMSGLA VLSNYSSYFA QVAGFSDPFV
FSLLLAIVAI LITILICLTT DFIGRRAIFL GAVVVTWCML IIVGGMGLIK NPSHSINQLV
LFFSLVWRMS STCLGTLGWS YVAETGSGRL RAITAGVSAA GGVAIGTLFS TTVPYMLNAN
YANWGLKTCF FFAGVSAPMC IAAFFIMPDT SKRTPAELDE MFERKIKPWR FRSYVSDAQK
ALQAQKERTG ETDAVALQNA SNRR
//
