ID Q5KCP6_CRYNJ Unreviewed; 655 AA.
AC Q5KCP6;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 2.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=FCP1 homology domain-containing protein {ECO:0000259|SMART:SM00577};
GN OrderedLocusNames=CNH01800 {ECO:0000313|EMBL:AAW45047.2};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW45047.2, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW45047.2, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
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DR EMBL; AE017348; AAW45047.2; -; Genomic_DNA.
DR RefSeq; XP_572354.1; XM_572354.1.
DR AlphaFoldDB; Q5KCP6; -.
DR STRING; 214684.Q5KCP6; -.
DR PaxDb; 214684-Q5KCP6; -.
DR EnsemblFungi; AAW45047; AAW45047; CNH01800.
DR VEuPathDB; FungiDB:CNH01800; -.
DR eggNOG; KOG1605; Eukaryota.
DR HOGENOM; CLU_029716_0_0_1; -.
DR InParanoid; Q5KCP6; -.
DR OrthoDB; 856430at2759; -.
DR Proteomes; UP000002149; Chromosome 8.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IBA:GO_Central.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR004274; FCP1_dom.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR PANTHER; PTHR12210; DULLARD PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR12210:SF171; PHOSPHATASE HERZOG; 1.
DR SMART; SM00577; CPDc; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002149}.
FT DOMAIN 137..325
FT /note="FCP1 homology"
FT /evidence="ECO:0000259|SMART:SM00577"
FT REGION 32..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 332..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 575..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..97
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..116
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..482
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..606
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 613..643
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 655 AA; 74649 MW; BF4A8716C528CC29 CRC64;
MPKPHLKALA ITDLRPSFLS TISHAINMSF NRSSHHDDLP GQELERRPRH TRSGREWRRY
SPSWPVDFSS PPPDYRSYST SPVRTRLYHS RPSPSETTRG PWRPPPPPPV SFPPPHYVDL
ARPSTKKNKA LVKKTVTPKL LVLDLNGALV WRNRSYRAHM SNPRPYLSCF LEYLFLPEPS
SDNGNRPGDT QSVRPWEVFV WSSAQPHNVR AMVEACFGSR WIEGIWEQAS EEGKKGTEEG
EGRLLGVWAR DKMGLKGFDY SRKVQTTKDL RKVLSHLIET KKLPDPTTPY SEKTIVLLDD
SPLKAVFQPW NQIVIPEFDK ALHRSSRLAA GLKSDTHDDS DDGEASTSQT GQGHEMDKIL
LAVIGILDQL RHVSNVPLWV RAGGLTFDLD ETNLHPPTHE SLPSHVDYQH WFNDQEVYSK
WVAKGEEALK RKGIEVRHGL DIPPSPPSRE TQDGIFHVAP IASLRSPSLD SREEREESRA
RYSPSRPTSC LSPSSSDDRL DFEVSDGEME CTKSESAFAR RKREERAREK AARKVRKGQQ
QFARYAEHKV DEEAIKGEVH PGDIADLSIN ENAAVPSENK IDSKAPNEND IESVAARKEA
KQVRRKQTRA ERKVKKNEKE RELEELRRER KGEQASGEAP RKRASHLQRR HPLKE
//
