ID Q5KE85_CRYNJ Unreviewed; 324 AA.
AC Q5KE85; Q55P72;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=Hydrophilic protein, putative {ECO:0000313|EMBL:AAW44523.1};
GN OrderedLocusNames=CNG01380 {ECO:0000313|EMBL:AAW44523.1};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW44523.1, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW44523.1, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AE017347; AAW44523.1; -; Genomic_DNA.
DR RefSeq; XP_571830.1; XM_571830.1.
DR AlphaFoldDB; Q5KE85; -.
DR STRING; 214684.Q5KE85; -.
DR PaxDb; 214684-Q5KE85; -.
DR EnsemblFungi; AAW44523; AAW44523; CNG01380.
DR GeneID; 3258950; -.
DR KEGG; cne:CNG01380; -.
DR VEuPathDB; FungiDB:CNG01380; -.
DR eggNOG; KOG4017; Eukaryota.
DR HOGENOM; CLU_053731_0_1_1; -.
DR InParanoid; Q5KE85; -.
DR OMA; DEYTHTC; -.
DR OrthoDB; 1344100at2759; -.
DR Proteomes; UP000002149; Chromosome 7.
DR GO; GO:0000110; C:nucleotide-excision repair factor 1 complex; IBA:GO_Central.
DR GO; GO:0003684; F:damaged DNA binding; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:EnsemblFungi.
DR GO; GO:0006284; P:base-excision repair; IBA:GO_Central.
DR GO; GO:1901255; P:nucleotide-excision repair involved in interstrand cross-link repair; IBA:GO_Central.
DR GO; GO:0000715; P:nucleotide-excision repair, DNA damage recognition; IBA:GO_Central.
DR GO; GO:0070914; P:UV-damage excision repair; IBA:GO_Central.
DR CDD; cd21077; DBD_Rad14; 1.
DR Gene3D; 3.90.530.10; XPA C-terminal domain; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000465; XPA.
DR InterPro; IPR022656; XPA_C.
DR InterPro; IPR022658; XPA_CS.
DR InterPro; IPR037129; XPA_sf.
DR NCBIfam; TIGR00598; rad14; 1.
DR PANTHER; PTHR10142; DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS; 1.
DR PANTHER; PTHR10142:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS; 1.
DR Pfam; PF05181; XPA_C; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS00753; XPA_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002149};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 181..231
FT /note="XPA C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05181"
FT REGION 26..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 324 AA; 37345 MW; 876C699875C0ADC2 CRC64;
MSAPTTAPVL TPDQARLAAL NRLKAKNKLT ANTTGGNAAG PSNGNHGNAG PAYVNRREAI
PSSARNMVQQ QAEADKAKPL PLRRDPSLGK YFEYDLSKMR NSRGGFLTEE DKEGDRIKSV
AELAREKERQ LQMIREGEEP AIIPDRSPRC VECGTLEINY QFLKVFDVRV CKSCEKKLPE
KYSLLTKTEC KEDYLLTDPE LKDVDLLPHL LRPNPHASTY SNMMLFLREQ VEKVAFQKWG
GEEGLDNEWK RREEFKKRKR EEKFEQGLRD LRKRTRNNLY QRKQEAQHVH EFEDVEEVYD
EQEQTTKLLQ RCFGCGSEQE VEVL
//
