ID Q5KIF4_CRYNJ Unreviewed; 458 AA.
AC Q5KIF4; Q55TY4;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 2.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Long-chain fatty acid transporter, putative {ECO:0000313|EMBL:AAW43208.2};
GN OrderedLocusNames=CND03160 {ECO:0000313|EMBL:AAW43208.2};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW43208.2, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW43208.2, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
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DR EMBL; AE017344; AAW43208.2; -; Genomic_DNA.
DR RefSeq; XP_570515.1; XM_570515.1.
DR AlphaFoldDB; Q5KIF4; -.
DR SMR; Q5KIF4; -.
DR STRING; 214684.Q5KIF4; -.
DR PaxDb; 214684-Q5KIF4; -.
DR EnsemblFungi; AAW43208; AAW43208; CND03160.
DR VEuPathDB; FungiDB:CND03160; -.
DR HOGENOM; CLU_597184_0_0_1; -.
DR InParanoid; Q5KIF4; -.
DR OrthoDB; 948481at2759; -.
DR Proteomes; UP000002149; Chromosome 4.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000062; F:fatty-acyl-CoA binding; IBA:GO_Central.
DR GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR Gene3D; 1.20.80.10; -; 1.
DR InterPro; IPR000582; Acyl-CoA-binding_protein.
DR InterPro; IPR035984; Acyl-CoA-binding_sf.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR PANTHER; PTHR23310:SF143; ACB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23310; ACYL-COA-BINDING PROTEIN, ACBP; 1.
DR Pfam; PF00887; ACBP; 1.
DR PRINTS; PR00689; ACOABINDINGP.
DR SUPFAM; SSF47027; Acyl-CoA binding protein; 1.
DR PROSITE; PS51228; ACB_2; 1.
PE 4: Predicted;
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002149};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 415..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..97
FT /note="ACB"
FT /evidence="ECO:0000259|PROSITE:PS51228"
FT REGION 125..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..174
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 458 AA; 51111 MW; AFCE5AEE0F8B86E1 CRC64;
MDSATAGLDA QFNRAVDIVQ SLPKGGTIQT TYEDKLWLYS LYKQAIEGDV AVPRPGMLDL
LGKAKWDAWN RQKGIDKPQA KRLYVSALVK ILRKCADAKD VQRYLQILEH ESGYEYPLHI
PSCPASPASS ASSYHSSQAS PALLPQSSNS PIVPPHDISP LTPSLPPPDD APNFIPPSSH
HSRNPPSLSS MQEQRNEVLD AVGRTGRDGN MRDQRPSSAQ NLTSESQIHA AMPLDRITGI
EREAVSGKSG SVHSPRRQRR DSQASARLAS PLPHPTVGSR DFLGTPETIS SPFLGLNQPT
PMYSRRPGST STFSNSQATN IPYTLQQIQT SLTALHERLS TLERTQALIL RRDERRKSWF
SWEGHESEEL DNCENDQAKE MWGRTGVTTV TKVNAKKKSI SMRVLWFLVK TLRRALMDVG
IGMMVTLIVI MVLNGGWGRA RWMILKYKER LRRFLTEQ
//
