ID Q5KLG3_CRYNJ Unreviewed; 159 AA.
AC Q5KLG3; Q55YH7;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 24-JAN-2024, entry version 90.
DE SubName: Full=Suppressor of initiator codon mutations, putative {ECO:0000313|EMBL:AAW41975.1};
GN OrderedLocusNames=CNB05380 {ECO:0000313|EMBL:AAW41975.1};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW41975.1, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW41975.1, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
CC -!- SIMILARITY: Belongs to the SUI1 family.
CC {ECO:0000256|ARBA:ARBA00005422}.
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DR EMBL; AE017342; AAW41975.1; -; Genomic_DNA.
DR RefSeq; XP_569282.1; XM_569282.1.
DR AlphaFoldDB; Q5KLG3; -.
DR STRING; 214684.Q5KLG3; -.
DR PaxDb; 214684-Q5KLG3; -.
DR EnsemblFungi; AAW41975; AAW41975; CNB05380.
DR GeneID; 3256035; -.
DR KEGG; cne:CNB05380; -.
DR VEuPathDB; FungiDB:CNB05380; -.
DR eggNOG; KOG1770; Eukaryota.
DR HOGENOM; CLU_082805_3_2_1; -.
DR InParanoid; Q5KLG3; -.
DR OMA; CEFMITQ; -.
DR OrthoDB; 1329568at2759; -.
DR Proteomes; UP000002149; Chromosome 2.
DR GO; GO:0016282; C:eukaryotic 43S preinitiation complex; IBA:GO_Central.
DR GO; GO:0043614; C:multi-eIF complex; IEA:EnsemblFungi.
DR GO; GO:0043024; F:ribosomal small subunit binding; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR GO; GO:0031369; F:translation initiation factor binding; IEA:EnsemblFungi.
DR GO; GO:0001731; P:formation of translation preinitiation complex; IEA:EnsemblFungi.
DR GO; GO:1990145; P:maintenance of translational fidelity; IEA:EnsemblFungi.
DR GO; GO:0006450; P:regulation of translational fidelity; IEA:EnsemblFungi.
DR CDD; cd11566; eIF1_SUI1; 1.
DR Gene3D; 3.30.780.10; SUI1-like domain; 1.
DR InterPro; IPR001950; SUI1.
DR InterPro; IPR036877; SUI1_dom_sf.
DR InterPro; IPR005874; SUI1_euk.
DR PANTHER; PTHR10388:SF4; EUKARYOTIC TRANSLATION INITIATION FACTOR EIF1; 1.
DR PANTHER; PTHR10388; EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1; 1.
DR Pfam; PF01253; SUI1; 1.
DR PIRSF; PIRSF004499; SUI1_euk; 1.
DR SUPFAM; SSF55159; eIF1-like; 1.
DR PROSITE; PS50296; SUI1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002149}.
FT DOMAIN 59..143
FT /note="SUI1"
FT /evidence="ECO:0000259|PROSITE:PS50296"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 159 AA; 17061 MW; 0DF5462CE0F85F81 CRC64;
MSTTVTQSKV DATTKKTKAP AATAGVENLG PAFDPFAPVN DLNDTPSIEK AVGSKNDKIH
IRLQQRNGRK TLTTVQGIPS KYNHSKILKA MKKEFACNGT VVKPEVDSGE EDSPAPVAKN
HGDVLQLQGD QRVAAKQFLI DSGIVAQKEA KDLIVVHGY
//
