ID Q5KNG7_CRYNJ Unreviewed; 346 AA.
AC Q5KNG7;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 2.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=YDG domain-containing protein {ECO:0000259|PROSITE:PS51015};
GN OrderedLocusNames=CNA06550 {ECO:0000313|EMBL:AAW41176.2};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW41176.2, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW41176.2, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00358}.
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DR EMBL; AE017341; AAW41176.2; -; Genomic_DNA.
DR RefSeq; XP_566995.1; XM_566995.1.
DR AlphaFoldDB; Q5KNG7; -.
DR STRING; 214684.Q5KNG7; -.
DR PaxDb; 214684-Q5KNG7; -.
DR EnsemblFungi; AAW41176; AAW41176; CNA06550.
DR VEuPathDB; FungiDB:CNA06550; -.
DR eggNOG; ENOG502QRDQ; Eukaryota.
DR HOGENOM; CLU_090083_1_1_1; -.
DR InParanoid; Q5KNG7; -.
DR OrthoDB; 5481936at2759; -.
DR Proteomes; UP000002149; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR Gene3D; 2.30.280.10; SRA-YDG; 1.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036987; SRA-YDG_sf.
DR InterPro; IPR003105; SRA_YDG.
DR InterPro; IPR045134; UHRF1/2-like.
DR PANTHER; PTHR14140; E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED; 1.
DR PANTHER; PTHR14140:SF27; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR Pfam; PF02182; SAD_SRA; 1.
DR SMART; SM00466; SRA; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS51015; YDG; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00358}; Reference proteome {ECO:0000313|Proteomes:UP000002149}.
FT DOMAIN 167..321
FT /note="YDG"
FT /evidence="ECO:0000259|PROSITE:PS51015"
FT REGION 40..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 325..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..256
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 346 AA; 38600 MW; 337537B09CCA0482 CRC64;
MTDTEKSQLS LMNLTYEEQR LENIRKNEEL LRSLGLETPS EAKSLATPSS LKTAGKQRRY
DDGLAGESNT ARNRPGFPRK QRTNDVEDLT LVPHSAVKRR RSVRLGGREK PNYTKELVTF
NGDRDTPNTP SRYIKSTHSH PDSEEGDIRQ GKISKLGVRL HNPKTFGHIP GVEVGKWWAT
RMEASADAVH APTVAGISGN ANDGAWSVAL SGGYPDDIDL GYAFTYTGCG GRDLKGTKQN
PKNLRTAPQT SHQSFDNPLN AALKRSAETR NPVRVIRGFK LQSKYAPPTG YRYDGLYVVE
KAWMAKGLTN GLMVCRYAFK RMDDQEPLPE RDLDHDDDND KARPSE
//
