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Database: UniProt
Entry: Q5KYV3_GEOKA
LinkDB: Q5KYV3_GEOKA
Original site: Q5KYV3_GEOKA 
ID   Q5KYV3_GEOKA            Unreviewed;       664 AA.
AC   Q5KYV3;
DT   01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   01-FEB-2005, sequence version 1.
DT   07-OCT-2020, entry version 99.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   OrderedLocusNames=GK1848 {ECO:0000313|EMBL:BAD76133.1};
OS   Geobacillus kaustophilus (strain HTA426).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC   Geobacillus thermoleovorans group.
OX   NCBI_TaxID=235909 {ECO:0000313|EMBL:BAD76133.1, ECO:0000313|Proteomes:UP000001172};
RN   [1] {ECO:0000313|EMBL:BAD76133.1, ECO:0000313|Proteomes:UP000001172}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTA426 {ECO:0000313|EMBL:BAD76133.1,
RC   ECO:0000313|Proteomes:UP000001172};
RX   PubMed=15576355; DOI=10.1093/nar/gkh970;
RA   Takami H., Takaki Y., Chee G.J., Nishi S., Shimamura S., Suzuki H.,
RA   Matsui S., Uchiyama I.;
RT   "Thermoadaptation trait revealed by the genome sequence of thermophilic
RT   Geobacillus kaustophilus.";
RL   Nucleic Acids Res. 32:6292-6303(2004).
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake system.
CC       {ECO:0000256|ARBA:ARBA00003926, ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362098}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
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DR   EMBL; BA000043; BAD76133.1; -; Genomic_DNA.
DR   RefSeq; WP_011231338.1; NC_006510.1.
DR   STRING; 235909.GK1848; -.
DR   EnsemblBacteria; BAD76133; BAD76133; GK1848.
DR   KEGG; gka:GK1848; -.
DR   PATRIC; fig|235909.7.peg.1980; -.
DR   eggNOG; COG0370; Bacteria.
DR   HOGENOM; CLU_013350_3_0_9; -.
DR   KO; K04759; -.
DR   OMA; PLGYDWK; -.
DR   Proteomes; UP000001172; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001172};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM        277..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        339..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        383..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        417..443
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        449..469
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        507..528
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        540..558
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        605..625
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        637..658
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   DOMAIN          1..161
FT                   /note="FeoB-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51711"
SQ   SEQUENCE   664 AA;  72389 MW;  F6EE671DA01D71E6 CRC64;
     MSYVALFGNP NTGKTSLFNC LTGSYEYVGN WSGVTVEKKV GVLRQHGVPV VDLPGVYSLQ
     PLSRDEGVAT DFLLTEPCSA IVNIVDASQL RRNLHLTVQL LEFGRPLVIA LNMVDVAEKR
     GVKVDAAKLS KYLGVPVIPV IARTGKGTNE LVHAVLAAKD KPHSSIAIDY GVEVENAIRC
     ITERLPDDVP GDKRWVALQF LEGNERMAAY LRGRLDLSPL LEARAEAEQK LGSSVAEQIY
     ETRDRWIGEA IAVAAMALEN KPLTWTEKID VVVTNRYVGL PIFLALMYLV FMLTFNWLGT
     PLADQLDAFF SGPLTDWLSR LLDWAGASPF IKALILDGIV AGVGGVLVFV PQIFILFFFI
     SLLEDSGYMA RVAMVMDRMM EAIGLNGKAF IPMIIGFGCN VPGVMAARTI EQPKERLLTI
     LLLPFMSCSA RLPVYALFAG TFFVREQALV VFSLYVLGIV VALGLAKLFS STLLKNESSL
     FVIELPPYRV PQALTLWRST WEKGKGFVRK AGTFIFGGSV AIWLLTYIGP HGVGVAMDDS
     FLAAIGGLIA PLLAPLGFGA WQAGAALITG FLAKEVVVST MNIIYHVHEA NGLKQVIASH
     FTPLSAFSFM VFVLLYTPCL ATVAAIRKET GARKWTLLSI GCALTVAYVI SFAVYQFGHM
     LGYS
//
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