ID   Q5L7T1_BACFN            Unreviewed;       601 AA.
AC   Q5L7T1; A0A380YU08;
DT   21-JUN-2005, integrated into UniProtKB/TrEMBL.
DT   21-JUN-2005, sequence version 1.
DT   27-MAR-2024, entry version 103.
DE   RecName: Full=Aminotransferase {ECO:0000256|RuleBase:RU000481};
DE            EC=2.6.1.- {ECO:0000256|RuleBase:RU000481};
GN   ORFNames=BF9343_4087 {ECO:0000313|EMBL:CAH09868.1};
OS   Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019
OS   / NCTC 9343 / Onslow).
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=272559 {ECO:0000313|EMBL:CAH09868.1, ECO:0000313|Proteomes:UP000006731};
RN   [1] {ECO:0000313|EMBL:CAH09868.1, ECO:0000313|Proteomes:UP000006731}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 /
RC   Onslow {ECO:0000313|Proteomes:UP000006731};
RX   PubMed=15746427; DOI=10.1126/science.1107008;
RA   Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G., Abratt V.,
RA   Lennard N., Poxton I., Duerden B., Harris B., Quail M.A., Barron A.,
RA   Clark L., Corton C., Doggett J., Holden M.T.G., Larke N., Line A., Lord A.,
RA   Norbertczak H., Ormond D., Price C., Rabbinowitsch E., Woodward J.,
RA   Barrell B.G., Parkhill J.;
RT   "Extensive DNA inversions in the B. fragilis genome control variable gene
RT   expression.";
RL   Science 307:1463-1465(2005).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|RuleBase:RU000481};
CC   -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|RuleBase:RU000481}.
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DR   EMBL; CR626927; CAH09868.1; -; Genomic_DNA.
DR   RefSeq; WP_010993752.1; NZ_UFTH01000001.1.
DR   PaxDb; 272559-BF9343_4087; -.
DR   KEGG; bfs:BF9343_4087; -.
DR   eggNOG; COG0079; Bacteria.
DR   eggNOG; COG1213; Bacteria.
DR   HOGENOM; CLU_451177_0_0_10; -.
DR   BioCyc; BFRA272559:G1GHZ-4513-MONOMER; -.
DR   Proteomes; UP000006731; Chromosome.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   CDD; cd02523; PC_cytidylyltransferase; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR025877; MobA-like_NTP_Trfase.
DR   InterPro; IPR004838; NHTrfase_class1_PyrdxlP-BS.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR42885; HISTIDINOL-PHOSPHATE AMINOTRANSFERASE-RELATED; 1.
DR   PANTHER; PTHR42885:SF1; THREONINE-PHOSPHATE DECARBOXYLASE; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   Pfam; PF12804; NTP_transf_3; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00105; AA_TRANSFER_CLASS_1; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000256|RuleBase:RU000481};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006731};
KW   Transferase {ECO:0000256|RuleBase:RU000481}.
FT   DOMAIN          3..130
FT                   /note="MobA-like NTP transferase"
FT                   /evidence="ECO:0000259|Pfam:PF12804"
FT   DOMAIN          300..595
FT                   /note="Aminotransferase class I/classII"
FT                   /evidence="ECO:0000259|Pfam:PF00155"
SQ   SEQUENCE   601 AA;  69463 MW;  27A25DF90D1F8D38 CRC64;
     MQAIILAAGM GRRLGELTRY DTKCMIEVNG IRIIDRLLAN LAVARLSRIV LVIGFQGDKL
     RAYLGNEYCG IPIYYLENPY YAYTNNIYSL FLARHHLASD DTLLLESDIV FEKRILERVL
     EEPYPDVAVV DRYKSWMDGT MVTVDEKQFI VDFVSKHTFS YEKTSTYFKT VNIYRFSKEF
     SVGKYVPFLE AYCKCFDNSA YYEQILAVLS LLDKAGLKAL PLEGEKWYEI DDMQDLDIAE
     TLFGKKEGLL SGYQKRYGGY WRFPFLFDFA YLVNPHFPTE RMLEELKANF DKLLRQYPSG
     SYVNRRLVAK HWNIPAEAVA VGNGAAELIR KLMELLPGRM GVILPTFEEY LVRDDRIETF
     LPLGPGYRYT VSDLKTFFED KGVTSLLLLN PDNPSGNSIP YEDLISLAGW TQERSIRLIV
     DESFIDFSEG GEETSLIDDK ILKEYNHLVV IKSLSKSHGI PGLRLGIAVS GDHKLMDELQ
     QKLPVWNINS LAEYYLQILD KYTIAYRQAC ARFREERALF FEELQEVGYL AVFPSQANFF
     LCEVTHKYSA RELAEVLLRE HDILVKDCSL KRGMYGKQYI RIAIRSKEEN RYLAGILKYK
     L
//