ID Q5L886_BACFN Unreviewed; 592 AA.
AC Q5L886; A0A380YUK8;
DT 21-JUN-2005, integrated into UniProtKB/TrEMBL.
DT 21-JUN-2005, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Peptidase {ECO:0000313|EMBL:CAH09702.1};
DE EC=3.4.11.9 {ECO:0000313|EMBL:CAH09702.1};
GN ORFNames=BF9343_3921 {ECO:0000313|EMBL:CAH09702.1};
OS Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019
OS / NCTC 9343 / Onslow).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=272559 {ECO:0000313|EMBL:CAH09702.1, ECO:0000313|Proteomes:UP000006731};
RN [1] {ECO:0000313|EMBL:CAH09702.1, ECO:0000313|Proteomes:UP000006731}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 /
RC Onslow {ECO:0000313|Proteomes:UP000006731};
RX PubMed=15746427; DOI=10.1126/science.1107008;
RA Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G., Abratt V.,
RA Lennard N., Poxton I., Duerden B., Harris B., Quail M.A., Barron A.,
RA Clark L., Corton C., Doggett J., Holden M.T.G., Larke N., Line A., Lord A.,
RA Norbertczak H., Ormond D., Price C., Rabbinowitsch E., Woodward J.,
RA Barrell B.G., Parkhill J.;
RT "Extensive DNA inversions in the B. fragilis genome control variable gene
RT expression.";
RL Science 307:1463-1465(2005).
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
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DR EMBL; CR626927; CAH09702.1; -; Genomic_DNA.
DR RefSeq; WP_010993671.1; NZ_UFTH01000001.1.
DR PaxDb; 272559-BF9343_3921; -.
DR KEGG; bfs:BF9343_3921; -.
DR eggNOG; COG0006; Bacteria.
DR HOGENOM; CLU_011781_2_4_10; -.
DR BioCyc; BFRA272559:G1GHZ-4310-MONOMER; -.
DR Proteomes; UP000006731; Chromosome.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:CAH09702.1};
KW Hydrolase {ECO:0000313|EMBL:CAH09702.1};
KW Protease {ECO:0000313|EMBL:CAH09702.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006731}.
FT DOMAIN 9..133
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 310..522
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 532..592
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 592 AA; 65900 MW; B76174E8B37B35E8 CRC64;
MKQSISERIH ALRMWFKPNI QAFIIPSTDP HLSEYVAPHW KSREWISGFT GSAGTVVITE
KKAGLWTDSR YFLQAAEQLQ GSGIDLYKEM LPETPSITKF LSDELQPGES VGIDGKMFSV
EQVESMQAEL SAKNIQIVFC PDPMDELWEN RPPMPESPAF VYDIKYAGKS CSEKIAAIRT
ELKKKSAESV MLSALDEIAW TLNLRGNDVH CNPVVVSYLL ITEKKAVLFI APEKVTEGVR
NYLEEQQIEI QNYSDTEIYL SDLNSSSILM NPAKTNYSVF SSVNPRCRII RGEAPVALLK
AIRNDQEIKG IHAAMQRDGV ALVKFLRWLE SAVPSGTETE LSIDRKLHAF RATQDLYAGE
SFDTIAGYKE HGAIVHYSAT EESNATLHPK GFLLLDSGAQ YLDGTTDITR TIALGELTTE
EKTDYTLVLK GHIALAMAVF PSGTRGAQLD VLARMPLWSH KMNFLHGTGH GVGHFLSVHE
GPQSIRMNEN PIVLQPGMVT SNEPGVYKGG SHGIRTENLT LVCSAGEGLF GEYLKFETIT
LCPICKKGII KELLTADEVD WLNNYHQQVY EKLSPKLNEE EKAWLKEATA AI
//
