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Database: UniProt
Entry: Q5L8P9_BACFN
LinkDB: Q5L8P9_BACFN
Original site: Q5L8P9_BACFN 
ID   Q5L8P9_BACFN            Unreviewed;       822 AA.
AC   Q5L8P9;
DT   21-JUN-2005, integrated into UniProtKB/TrEMBL.
DT   21-JUN-2005, sequence version 1.
DT   08-MAY-2019, entry version 89.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=BF9343_3753 {ECO:0000313|EMBL:CAH09534.1};
OS   Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 /
OS   NCTC 9343).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=272559 {ECO:0000313|EMBL:CAH09534.1, ECO:0000313|Proteomes:UP000006731};
RN   [1] {ECO:0000313|EMBL:CAH09534.1, ECO:0000313|Proteomes:UP000006731}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343
RC   {ECO:0000313|Proteomes:UP000006731};
RX   PubMed=15746427; DOI=10.1126/science.1107008;
RA   Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G.,
RA   Abratt V., Lennard N., Poxton I., Duerden B., Harris B., Quail M.A.,
RA   Barron A., Clark L., Corton C., Doggett J., Holden M.T.G., Larke N.,
RA   Line A., Lord A., Norbertczak H., Ormond D., Price C.,
RA   Rabbinowitsch E., Woodward J., Barrell B.G., Parkhill J.;
RT   "Extensive DNA inversions in the B. fragilis genome control variable
RT   gene expression.";
RL   Science 307:1463-1465(2005).
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU362098}.
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DR   EMBL; CR626927; CAH09534.1; -; Genomic_DNA.
DR   RefSeq; WP_010993617.1; NC_003228.3.
DR   STRING; 272559.BF9343_3753; -.
DR   EnsemblBacteria; CAH09534; CAH09534; BF9343_3753.
DR   KEGG; bfs:BF9343_3753; -.
DR   eggNOG; ENOG4105CE1; Bacteria.
DR   eggNOG; COG0370; LUCA.
DR   HOGENOM; HOG000054021; -.
DR   OMA; MEMPDYE; -.
DR   OrthoDB; 304844at2; -.
DR   BioCyc; BFRA272559:G1GHZ-4105-MONOMER; -.
DR   Proteomes; UP000006731; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   Gene3D; 2.30.30.90; -; 1.
DR   InterPro; IPR007167; Fe-transptr_FeoA.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR038157; FeoA_core_dom.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR008988; Transcriptional_repressor_C.
DR   Pfam; PF04023; FeoA; 1.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SMART; SM00899; FeoA; 1.
DR   SUPFAM; SSF50037; SSF50037; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000006731};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006731};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    440    461       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    490    517       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    547    567       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    606    626       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    664    685       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    764    786       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    795    817       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN      109    271       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   822 AA;  93252 MW;  2F1C2709F1C1C213 CRC64;
     MRLSELKTGE KGIIVKVLGH GGFRKRIVEM GFIKGKTIAV ILNAPLKDPI KYSLLGYEIS
     LRRQEAEMIE VVSEQETRTT QDSYYGPIIE ETMIPENKMA TLAKGKRRTI NVALIGNPNC
     GKTSLFNYAS GAHERIGNYS GVTVDAKENA FDFQGYHFRI VDLPGTYSLS TYTPEEVYVR
     KYIIEETPDV IINVVDASNL ERNFYLTTQL IDMNVRMVVA LNMFDELKAS GNQLDYLKLS
     RLLGVPMVPT VCRTGEGVDK LFHIIISLYE GIDFLTQEKL DVRTEVLEDL KGWHETYVPD
     HEFGSHSEEV HIKSHAYFRH IHINHGPELE RSIEAVKKLI SDNKQIRHKY STRFLAIKLL
     EKDKDIELFV KTLPNGSEIL ALRDKETQRL YKAINEDSEQ AITDAKYGFI AGALKETFVN
     NQKEKEQVTR IIDTIVTHHI WGYPIFFLFL YIMFEVTFVF GNYPMQGIEW LVEQLGNQIR
     NNMTEGPLKA LLVDGIIGGV GGVIVFLPNI LILYFFISIM EDSGYMARAA FIMDKIMHRM
     GLHGKSFIPL IMGFGCNVPA IMSSRIIEDR KCRIITMLIN PLMSCSARLP IYLVMTQAFF
     PSHAGFILLC VYSTGILLAV FMARIFSKLL MKGDDAPFVM ELPPYRMPTA KSIFRHTWEK
     GNHYLRKMGS IIMVASIIIW FLGYYPHDNY ETVAEQQENS YIGQIGKAIE PMIEPLGFDW
     KLGVGLISGI GAKELVVSTL GVLYTNESDI ENVNLSNRIP ITPLVALTYM LFVLIYFPCI
     ATLIAIKQES GSWKWALFSM GYTLVLAWGL AFTVYQLGSL IV
//
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