GenomeNet

Database: UniProt
Entry: Q5LFK0_BACFN
LinkDB: Q5LFK0_BACFN
Original site: Q5LFK0_BACFN 
ID   Q5LFK0_BACFN            Unreviewed;       259 AA.
AC   Q5LFK0;
DT   21-JUN-2005, integrated into UniProtKB/TrEMBL.
DT   21-JUN-2005, sequence version 1.
DT   08-MAY-2019, entry version 72.
DE   SubName: Full=Putative methyltransferase protein {ECO:0000313|EMBL:CAH07093.1};
GN   ORFNames=BF9343_1312 {ECO:0000313|EMBL:CAH07093.1};
OS   Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 /
OS   NCTC 9343).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=272559 {ECO:0000313|EMBL:CAH07093.1, ECO:0000313|Proteomes:UP000006731};
RN   [1] {ECO:0000313|EMBL:CAH07093.1, ECO:0000313|Proteomes:UP000006731}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343
RC   {ECO:0000313|Proteomes:UP000006731};
RX   PubMed=15746427; DOI=10.1126/science.1107008;
RA   Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G.,
RA   Abratt V., Lennard N., Poxton I., Duerden B., Harris B., Quail M.A.,
RA   Barron A., Clark L., Corton C., Doggett J., Holden M.T.G., Larke N.,
RA   Line A., Lord A., Norbertczak H., Ormond D., Price C.,
RA   Rabbinowitsch E., Woodward J., Barrell B.G., Parkhill J.;
RT   "Extensive DNA inversions in the B. fragilis genome control variable
RT   gene expression.";
RL   Science 307:1463-1465(2005).
RN   [2] {ECO:0000213|PDB:5BP9}
RP   X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) OF 2-259 IN COMPLEX WITH
RP   S-ADENOSYL-L-HOMOCYSTEINE.
RA   Gasiorowska O.A., Shabalin I.G., Handing K.B., Cymborowski M.T.,
RA   Mason D., Bonanno J., Seidel R., Almo S.C., Minor W.;
RT   "Crystal structure of SAM-dependent methyltransferase fromBacteroides
RT   fragilis in complex with S-Adenosyl-L-homocysteine.";
RL   Submitted (MAY-2015) to the PDB data bank.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CR626927; CAH07093.1; -; Genomic_DNA.
DR   PDB; 5BP9; X-ray; 1.50 A; A=2-259.
DR   PDBsum; 5BP9; -.
DR   SMR; Q5LFK0; -.
DR   STRING; 272559.BF9343_1312; -.
DR   EnsemblBacteria; CAH07093; CAH07093; BF9343_1312.
DR   KEGG; bfs:BF9343_1312; -.
DR   eggNOG; ENOG4108P18; Bacteria.
DR   eggNOG; COG0500; LUCA.
DR   HOGENOM; HOG000032191; -.
DR   OMA; MNGTGIF; -.
DR   BioCyc; BFRA272559:G1GHZ-1417-MONOMER; -.
DR   Proteomes; UP000006731; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR029063; SAM-dependent_MTases.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0000213|PDB:5BP9};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006731};
KW   Methyltransferase {ECO:0000313|EMBL:CAH07093.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006731};
KW   Transferase {ECO:0000313|EMBL:CAH07093.1}.
FT   REGION       87     88       S-adenosyl-L-homocysteine binding.
FT                                {ECO:0000213|PDB:5BP9}.
FT   REGION      129    130       S-adenosyl-L-homocysteine binding.
FT                                {ECO:0000213|PDB:5BP9}.
FT   BINDING      63     63       S-adenosyl-L-homocysteine.
FT                                {ECO:0000213|PDB:5BP9}.
FT   BINDING     108    108       S-adenosyl-L-homocysteine.
FT                                {ECO:0000213|PDB:5BP9}.
SQ   SEQUENCE   259 AA;  29057 MW;  3201343AEAF3D83B CRC64;
     MNSLSLPAVT TKNQSMNTSL LPAEKDPMGA AIADFYHRQK ADRLRVFSSQ FDEDEIPVKQ
     LFRKAGQMPL LERTALAMAT GTILDVGAGS GCHALALQES GKEVSAIDIS PLSVEVMKLR
     GVKDARQVNL FDERFAATFD TILMLMNGSG IIGRLENMPL FFRKMKQLLR PDGCILMDSS
     DLRYLFEDED GSFLIDLAGD YYGEIDFRMQ YKDIQGDPFD WLYIDFQTLS AYAADNGFKA
     EMIKEGKHYD YLARLTVAL
//
DBGET integrated database retrieval system