ID Q5LFL0_BACFN Unreviewed; 364 AA.
AC Q5LFL0;
DT 21-JUN-2005, integrated into UniProtKB/TrEMBL.
DT 21-JUN-2005, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=LPS biosynthesis related UDP-galactopyranose mutase {ECO:0000313|EMBL:CAH07083.1};
GN Name=wcfM {ECO:0000313|EMBL:CAH07083.1};
GN ORFNames=BF9343_1302 {ECO:0000313|EMBL:CAH07083.1};
OS Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019
OS / NCTC 9343 / Onslow).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=272559 {ECO:0000313|EMBL:CAH07083.1, ECO:0000313|Proteomes:UP000006731};
RN [1] {ECO:0000313|EMBL:CAH07083.1, ECO:0000313|Proteomes:UP000006731}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 /
RC Onslow {ECO:0000313|Proteomes:UP000006731};
RX PubMed=15746427; DOI=10.1126/science.1107008;
RA Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G., Abratt V.,
RA Lennard N., Poxton I., Duerden B., Harris B., Quail M.A., Barron A.,
RA Clark L., Corton C., Doggett J., Holden M.T.G., Larke N., Line A., Lord A.,
RA Norbertczak H., Ormond D., Price C., Rabbinowitsch E., Woodward J.,
RA Barrell B.G., Parkhill J.;
RT "Extensive DNA inversions in the B. fragilis genome control variable gene
RT expression.";
RL Science 307:1463-1465(2005).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase
CC family. {ECO:0000256|ARBA:ARBA00009321}.
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DR EMBL; CR626927; CAH07083.1; -; Genomic_DNA.
DR RefSeq; WP_005786166.1; NZ_UFTH01000001.1.
DR PaxDb; 272559-BF9343_1302; -.
DR KEGG; bfs:BF9343_1302; -.
DR eggNOG; COG0562; Bacteria.
DR HOGENOM; CLU_042118_0_0_10; -.
DR BioCyc; BFRA272559:G1GHZ-1406-MONOMER; -.
DR Proteomes; UP000006731; Chromosome.
DR GO; GO:0008767; F:UDP-galactopyranose mutase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 3.
DR InterPro; IPR004379; UDP-GALP_mutase.
DR InterPro; IPR015899; UDP-GalPyranose_mutase_C.
DR NCBIfam; TIGR00031; UDP-GALP_mutase; 1.
DR PANTHER; PTHR21197; UDP-GALACTOPYRANOSE MUTASE; 1.
DR PANTHER; PTHR21197:SF0; UDP-GALACTOPYRANOSE MUTASE; 1.
DR Pfam; PF03275; GLF; 1.
DR Pfam; PF13450; NAD_binding_8; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000006731}.
FT DOMAIN 150..349
FT /note="UDP-galactopyranose mutase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03275"
SQ SEQUENCE 364 AA; 42692 MW; 0E345098C0EDDA40 CRC64;
MKKKYDYLIV GAGLYGSVFA YKAQRNGKKC LLIDKRPHNG GNIYCENIEG INVHKYGAHI
FHTSNKEVWD FVNAIVEFNR YTNSPIANYK GKLYNLPFNM NTFYALWGTK TPEEAKMKIE
EQRREAGILT PKNLEEQAIS LVGKDIYEIL IKGYTEKQWG RKATELPAFI IKRLPVRFTF
DNNYFNDKYQ GIPVGGYNKL INGLLDGIEV RTNTDFFQNK EYFKGLADKI LFTGKIDEYY
NYQFGRLEYR TVEFETQVLD CENYQGNAVV NYTEREVPYT RIIEHKHFEF GTQPKTVISK
EYSSEWKDGS EPFYPVNDER NNSLYLEYKK LVDREKNVLF GGRLAEYKYY DMNVIVEKVI
NSDL
//
