ID   Q5LG61_BACFN            Unreviewed;       723 AA.
AC   Q5LG61;
DT   21-JUN-2005, integrated into UniProtKB/TrEMBL.
DT   21-JUN-2005, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   SubName: Full=Alpha-glucosidase {ECO:0000313|EMBL:CAH06880.1};
GN   Name=susB {ECO:0000313|EMBL:CAH06880.1};
GN   ORFNames=BF9343_1099 {ECO:0000313|EMBL:CAH06880.1};
OS   Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019
OS   / NCTC 9343 / Onslow).
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=272559 {ECO:0000313|EMBL:CAH06880.1, ECO:0000313|Proteomes:UP000006731};
RN   [1] {ECO:0000313|EMBL:CAH06880.1, ECO:0000313|Proteomes:UP000006731}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 /
RC   Onslow {ECO:0000313|Proteomes:UP000006731};
RX   PubMed=15746427; DOI=10.1126/science.1107008;
RA   Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G., Abratt V.,
RA   Lennard N., Poxton I., Duerden B., Harris B., Quail M.A., Barron A.,
RA   Clark L., Corton C., Doggett J., Holden M.T.G., Larke N., Line A., Lord A.,
RA   Norbertczak H., Ormond D., Price C., Rabbinowitsch E., Woodward J.,
RA   Barrell B.G., Parkhill J.;
RT   "Extensive DNA inversions in the B. fragilis genome control variable gene
RT   expression.";
RL   Science 307:1463-1465(2005).
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
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DR   EMBL; CR626927; CAH06880.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q5LG61; -.
DR   CAZy; GH97; Glycoside Hydrolase Family 97.
DR   PaxDb; 272559-BF9343_1099; -.
DR   KEGG; bfs:BF9343_1099; -.
DR   eggNOG; COG1082; Bacteria.
DR   HOGENOM; CLU_011166_2_0_10; -.
DR   Proteomes; UP000006731; Chromosome.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   CDD; cd00063; FN3; 1.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR029483; GH97_C.
DR   InterPro; IPR019563; GH97_catalytic.
DR   InterPro; IPR029486; GH97_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR35803:SF1; GLUCAN 1,4-ALPHA-GLUCOSIDASE SUSB; 1.
DR   PANTHER; PTHR35803; GLUCAN 1,4-ALPHA-GLUCOSIDASE SUSB-RELATED; 1.
DR   Pfam; PF14509; GH97_C; 1.
DR   Pfam; PF14508; GH97_N; 1.
DR   Pfam; PF10566; Glyco_hydro_97; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006731};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           31..723
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004259271"
FT   DOMAIN          33..299
FT                   /note="Glycosyl-hydrolase 97 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14508"
FT   DOMAIN          304..605
FT                   /note="Glycosyl-hydrolase 97 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF10566"
FT   DOMAIN          608..708
FT                   /note="Glycosyl-hydrolase 97 C-terminal oligomerisation"
FT                   /evidence="ECO:0000259|Pfam:PF14509"
SQ   SEQUENCE   723 AA;  82392 MW;  C2D5785DD6101895 CRC64;
     MNHIMKNMKK LTFKLACFFL SLLVSSVAMA ESITSPNGLL KLNVSVNEKG EPVYELSYKG
     KEVIKPSKLG LELKDDPGLM DGFTLSDAKT SSFDETWEPV WGEVKQIRNN YNELAITLDQ
     KAQDRKMVIR FRLYNDGLGF RYEFPQQKNL NYFVIKEEHS QFAMAGDHTA FWIPGDYDTQ
     EYDYTRSKLS EIRGLMKTAV TPNASQTPFS PTGVQTALQM KTDDGLYINL HEAALVDYSC
     MHLNLDDKNF VFESWLTPDA QGTKGYMQTP CHSPWRTVMV SDDARDILAS KLTLNLNEPC
     KLEDTSWIKP VKYVGVWWEM ITGKSTWAYT DDVYSVKLGE TDYTKTKPNG RHGANNENVK
     RYIDFAAEHG FDQVLVEGWN EGWEDWFGKS KDYVFDFVTP YPDFDVKMLN EYARSKGVKL
     MMHHETSASV RNYERHMDEA YQFMEDNGYN AVKSGYVGNI IPRGEHHYGQ WLNNHYLYAV
     KKAADHKIMV NAHEAVRPTG LCRTYPNLIG NESARGTEYE AFGGNKPFHT TLLPFTRLIG
     GPMDYTPGIF DTQLSFLSGE HSFVHTTLAK QLALYVTLYS PLQMAADLPE SYERYMDAFQ
     FIKDVAVDWD ESKYIEAEPG EYITVARKAK NTNNWFVGGI TGENARTSTF VLDFLEPGKQ
     YVATLYADGK DADYEKNPTS YQIKKGLVTY KTKISTDLAR SGGFAISLIE ATPADKKALK
     KWK
//