ID Q5M4A1_STRT2 Unreviewed; 499 AA.
AC Q5M4A1;
DT 01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 01-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Exopolysaccharide biosynthesis protein, predicted membrane protein {ECO:0000313|EMBL:AAV60735.1};
GN Name=eps12 {ECO:0000313|EMBL:AAV60735.1};
GN OrderedLocusNames=stu1096 {ECO:0000313|EMBL:AAV60735.1};
OS Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=264199 {ECO:0000313|EMBL:AAV60735.1, ECO:0000313|Proteomes:UP000001170};
RN [1] {ECO:0000313|EMBL:AAV60735.1, ECO:0000313|Proteomes:UP000001170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-250 / LMG 18311 {ECO:0000313|Proteomes:UP000001170};
RX PubMed=15543133; DOI=10.1038/nbt1034;
RA Bolotin A., Quinquis B., Renault P., Sorokin A., Ehrlich S.D.,
RA Kulakauskas S., Lapidus A., Goltsman E., Mazur M., Pusch G.D., Fonstein M.,
RA Overbeek R., Kyprides N., Purnelle B., Prozzi D., Ngui K., Masuy D.,
RA Hancy F., Burteau S., Boutry M., Delcour J., Goffeau A., Hols P.;
RT "Complete sequence and comparative genome analysis of the dairy bacterium
RT Streptococcus thermophilus.";
RL Nat. Biotechnol. 22:1554-1558(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000023; AAV60735.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5M4A1; -.
DR STRING; 264199.stu1096; -.
DR KEGG; stl:stu1096; -.
DR PATRIC; fig|264199.4.peg.1073; -.
DR eggNOG; COG2244; Bacteria.
DR HOGENOM; CLU_040766_0_0_9; -.
DR Proteomes; UP000001170; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR029303; Polysacc_synt_C.
DR PANTHER; PTHR30250:SF11; INNER MEMBRANE PROTEIN YGHQ; 1.
DR PANTHER; PTHR30250; PST FAMILY PREDICTED COLANIC ACID TRANSPORTER; 1.
DR Pfam; PF14667; Polysacc_synt_C; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001170};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 47..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 344..480
FT /note="Polysaccharide biosynthesis protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14667"
SQ SEQUENCE 499 AA; 56613 MW; CF488A78DE18FFC1 CRC64;
MNRRKKFIYN SFSSLIKQLI GLLSTLILPR MMLVAYGSEV NGLVSSIGQF LALISLFDAG
MGVVIEASLY KPLALKDNLE INRVLSSGKR FYNKVVLLLL FYVVAISLFY PTFTEKNFSF
LYIFILIWAI SINLFGQYYF GVLNGVLISA DQKSYIFNWV YTFATLANTV LSVFLIKIGA
SIHIVELVSS IVFLIRPLLL AVYVKRNYNI NWSEKYDGEP IKQKWNGFTQ HLATIVVGNT
DVVVLTFFAS LKDISIYTIY IIVVNGLKEL VASSMGGVKS IFGDMLAKKE RQKLFVFFQA
VEFVSHWLVM FIYTASAILI VPFVSVYTKG IHDANYINIM FGVLISLAYA TYCLRIPYNT
LIMSAGHFKE TQNSALVEAT VNIVISVLLV FKFGLVGVAM GTLCAMIYRL FSLSLYANKK
ILQKNNFYTI KLFIFDILYF VFCNIVFKKL SVTICNSYLD WLLLSLKTGV MTFAIMTILV
SLFFRGEIKL LYNYKKGTL
//
