ID Q5M4V7_STRT2 Unreviewed; 623 AA.
AC Q5M4V7;
DT 01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 01-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 122.
DE SubName: Full=Lipid/multidrug/protein-type ABC exporter, ATP binding/membrane-spanning protein {ECO:0000313|EMBL:AAV60450.1};
GN OrderedLocusNames=stu0759 {ECO:0000313|EMBL:AAV60450.1};
OS Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=264199 {ECO:0000313|EMBL:AAV60450.1, ECO:0000313|Proteomes:UP000001170};
RN [1] {ECO:0000313|EMBL:AAV60450.1, ECO:0000313|Proteomes:UP000001170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-250 / LMG 18311 {ECO:0000313|Proteomes:UP000001170};
RX PubMed=15543133; DOI=10.1038/nbt1034;
RA Bolotin A., Quinquis B., Renault P., Sorokin A., Ehrlich S.D.,
RA Kulakauskas S., Lapidus A., Goltsman E., Mazur M., Pusch G.D., Fonstein M.,
RA Overbeek R., Kyprides N., Purnelle B., Prozzi D., Ngui K., Masuy D.,
RA Hancy F., Burteau S., Boutry M., Delcour J., Goffeau A., Hols P.;
RT "Complete sequence and comparative genome analysis of the dairy bacterium
RT Streptococcus thermophilus.";
RL Nat. Biotechnol. 22:1554-1558(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000023; AAV60450.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5M4V7; -.
DR STRING; 264199.stu0759; -.
DR KEGG; stl:stu0759; -.
DR eggNOG; COG1132; Bacteria.
DR HOGENOM; CLU_000604_84_4_9; -.
DR Proteomes; UP000001170; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18547; ABC_6TM_Tm288_like; 1.
DR CDD; cd03254; ABCC_Glucan_exporter_like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221:SF658; ABC TRANSPORTER B FAMILY MEMBER 29, CHLOROPLASTIC; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001170};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 62..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 66..349
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 383..617
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 623 AA; 70804 MW; A6B4597E5F84E387 CRC64;
MIKFWYLIRD IKLVLVIMKN CLPLIKSIKT FIILNIKRWS LMKARNNKST LKRLCKDILS
QCYLFALATV GTIVQVALTV YFPILLGDAV DAVLKMNAVF LMSRLIWQML LLILANSAIQ
WLNPLIYNRL IYSYSESLRE RVMMKIHAIP FSYLDRQGTG DMVSRVTTDS DQLNNGLLMF
FNQFFVGLLT IFVIIITMAR LDWFMMLLVL VMTPLSMLVT RFIARKSYQL YRNQTKWRGK
QTQLIEESLT QEALVQILNA QDQMVRNFNE VNGKYANYSQ GAIFYSSAVN PATRFFNSLL
YALITGVGAY RIMSGGTFTV GQLTTFLNYV TQYTKPFNDI SSVLSELQSA LACADRLYMI
LDEDEIPETG NAVLDEAEVQ GHFQFDHVQF GYLQNKPLIK DLSIDIPAAS TVAIVGPTGA
GKSTLINLLM RFYDLDKGQI LLDGRDITYY TRESLRKQIG MVLQETWLKV ATIHDNIAYG
NPKASREEVV AAAKAANADF FIKQLPLGYD TFLKDAGQSL SQGQRQLLTI ARIFVNVPKI
LILDEATSSI DTRTELLIQE AFAKLMKGRT SFIIAHRLST IENADLILVM NNGDIVEHGT
HNQLMRTKGM YYRMQTAQKT QNN
//
