ID Q5NEM5_FRATT Unreviewed; 679 AA.
AC Q5NEM5; A0A0G2RNH3;
DT 01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 01-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE RecName: Full=ATP-dependent DNA helicase RecG {ECO:0000256|ARBA:ARBA00017846};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN Name=recG {ECO:0000313|EMBL:CAG46234.1};
GN OrderedLocusNames=FTT_1601c {ECO:0000313|EMBL:CAG46234.1};
OS Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Francisellaceae; Francisella.
OX NCBI_TaxID=177416 {ECO:0000313|EMBL:CAG46234.1, ECO:0000313|Proteomes:UP000001174};
RN [1] {ECO:0000313|EMBL:CAG46234.1, ECO:0000313|Proteomes:UP000001174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCHU S4 / Schu 4 {ECO:0000313|Proteomes:UP000001174};
RX PubMed=15640799; DOI=10.1038/ng1499;
RA Larsson P., Oyston P.C.F., Chain P., Chu M., Duffield M., Fuxelius H.H.,
RA Garcia E., Halltorp G., Johansson D., Isherwood K., Karp P., Larsson E.,
RA Lui Y., Michell S., Prior J., Prior R., Sjostedt A., Svensson K.,
RA Thompson N., Vergez L., Wagg J., Wren B., Lindler L.E., Andersson S.G.,
RA Forsman M., Titball R.W.;
RT "The complete genome sequence of Francisella tularensis, the causative
RT agent of tularemia.";
RL Nat. Genet. 37:153-159(2005).
CC -!- SIMILARITY: Belongs to the helicase family. RecG subfamily.
CC {ECO:0000256|ARBA:ARBA00007504}.
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DR EMBL; AJ749949; CAG46234.1; -; Genomic_DNA.
DR RefSeq; WP_003022521.1; NZ_CP010290.1.
DR RefSeq; YP_170517.1; NC_006570.2.
DR AlphaFoldDB; Q5NEM5; -.
DR DNASU; 3191638; -.
DR EnsemblBacteria; CAG46234; CAG46234; FTT_1601c.
DR KEGG; ftu:FTT_1601c; -.
DR PATRIC; fig|177416.36.peg.1151; -.
DR OrthoDB; 9804325at2; -.
DR Proteomes; UP000001174; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd17992; DEXHc_RecG; 1.
DR CDD; cd04488; RecG_wedge_OBF; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047112; RecG/Mfd.
DR InterPro; IPR033454; RecG_wedge.
DR PANTHER; PTHR47964; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47964:SF1; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF17191; RecG_wedge; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CAG46234.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CAG46234.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001174}.
FT DOMAIN 267..434
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 467..614
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 679 AA; 77538 MW; AF2AA67DDA3736E1 CRC64;
MRFVDFNGVG EATIKALAKY NIHDPNDLLT IFPKDYKDTR VITPINHLVA GKRSLIQGRV
TNLTYKKFGK KFLRFNINDN TGFCSVILFK FYPNQLAILE KSEYVRCYGK VEFSLSPQMV
HPEWATVNNG ECALKQGFSA VYRLKKIPDR LISKMILKML QDNRVENIIP SQLLRRFNLI
SFCDALYYVH ALTNFIDEKY LSIARFSIKF EEMLAYKLAE QNIYKNTVKA QAPQLFLTKI
QQNEFYEKLP YQLTNAQQRA ITEILDDIKK SNAMNRLLQG DVGAGKTIVA TIAAYAAVKS
GYQVAMMAPT EILAEQHFSF LSQYLASFDI KVIPLLGKLS AKQTRESLDR IKDQKDCVVV
GTHAIFQERV EYCNLGLVIV DEQHRFGVEQ RLALVSKSSS NFSDLTPHQL IISATPIPRT
LAMTLYGNLK LSILDELPPK RKPIITTVLN RAKKQNLIEK VKQAVLRGEQ VYWVCPLVEE
SENMDFLQDV KTLYQELLEA LGKENVGLVY GSMKSKDKIE QMAAFKAKKY AVLVATTVIE
VGVDVPNATI MIIDNAERLG ISQLHQLRGR VGRGAKESYC ILLYSDKISE VGKRRLSLVR
ESQDGFYLAE KDLEIRGAGD IIGKEQSGVS TFKTFDINEY YDNYDKVVEF ADMLDKHYPE
LVDKLIQRWF DRRVNYVEV
//
