ID Q5NKS5_SORBI Unreviewed; 608 AA.
AC Q5NKS5;
DT 10-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 117.
DE RecName: Full=Starch synthase, chloroplastic/amyloplastic {ECO:0000256|RuleBase:RU361232};
DE EC=2.4.1.- {ECO:0000256|RuleBase:RU361232};
GN Name=131L1.8 {ECO:0000313|EMBL:AAQ06262.1};
GN ORFNames=SORBI_3010G022600 {ECO:0000313|EMBL:EER87785.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:AAQ06262.1};
RN [1] {ECO:0000313|EMBL:AAQ06262.1}
RP NUCLEOTIDE SEQUENCE.
RA Ma J., SanMiguel P.J., Dubcovsky J., Shiloff B.A., Rostoks N., Jiang Z.,
RA Busso C.S., Kleinhofs A., Devos K.M., Ramakrishna W., Bennetzen J.L.;
RT "Comparative sequence analysis of homologous Wx1 regions in barley, maize,
RT pearl millet, rice, sorghum and diploid wheat.";
RL Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABK80478.1}
RP NUCLEOTIDE SEQUENCE.
RA Hamblin M.T., Salas Fernandez M.G., Tuinstra M.R., Rooney W.L.,
RA Kresovich S.;
RT "Sequence variation at candidate loci in the starch metabolism pathway in
RT Sorghum bicolor: prospects for LD mapping.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EER87785.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [4] {ECO:0000313|EMBL:EER87785.1}
RP NUCLEOTIDE SEQUENCE.
RA Paterson A., Mullet J., Bowers J., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A., Chapman J., Feltus F.,
RA Gowik U., Grigoriev I., Lyons E., Maher C., Martis M., Narechania A.,
RA Otillar R., Penning B., Salamov A., Wang Y., Zhang L., Carpita N.,
RA Freeling M., Gingle A., Hash C., Keller B., Klein P., Kresovich S.,
RA Mccann M., Ming R., Peterson D., Rahman M., Ware D., Westhoff P., Mayer K.,
RA Messing J., Sims D., Jenkins J., Shu S., Rokhsar D.;
RT "WGS assembly of Sorghum bicolor.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + an NDP-alpha-D-glucose =
CC [(1->4)-alpha-D-glucosyl](n+1) + a ribonucleoside 5'-diphosphate +
CC H(+); Xref=Rhea:RHEA:15873, Rhea:RHEA-COMP:9584, Rhea:RHEA-COMP:9587,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:15444, ChEBI:CHEBI:57930,
CC ChEBI:CHEBI:76533; EC=2.4.1.242;
CC Evidence={ECO:0000256|ARBA:ARBA00036544};
CC -!- PATHWAY: Glycan biosynthesis; starch biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004727, ECO:0000256|RuleBase:RU361232}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000256|RuleBase:RU361232}. Plastid, amyloplast
CC {ECO:0000256|RuleBase:RU361232}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily.
CC {ECO:0000256|ARBA:ARBA00010281, ECO:0000256|RuleBase:RU361232}.
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DR EMBL; AF488412; AAQ06262.1; -; Genomic_DNA.
DR EMBL; EF089839; ABK80478.1; -; Genomic_DNA.
DR EMBL; EF089849; ABK80488.1; -; Genomic_DNA.
DR EMBL; EF089851; ABK80490.1; -; Genomic_DNA.
DR EMBL; CM000769; EER87785.1; -; Genomic_DNA.
DR RefSeq; XP_002436418.1; XM_002436373.1.
DR AlphaFoldDB; Q5NKS5; -.
DR SMR; Q5NKS5; -.
DR STRING; 4558.Q5NKS5; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblPlants; EER87785; EER87785; SORBI_3010G022600.
DR GeneID; 8068390; -.
DR Gramene; EER87785; EER87785; SORBI_3010G022600.
DR KEGG; sbi:8068390; -.
DR HOGENOM; CLU_009583_18_2_1; -.
DR InParanoid; Q5NKS5; -.
DR OMA; LGMTHPR; -.
DR OrthoDB; 141134at2759; -.
DR UniPathway; UPA00152; -.
DR Proteomes; UP000000768; Chromosome 10.
DR ExpressionAtlas; Q5NKS5; baseline.
DR GO; GO:0009501; C:amyloplast; IEA:UniProtKB-SubCell.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0043531; F:ADP binding; IEA:EnsemblPlants.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0019863; F:IgE binding; IEA:EnsemblPlants.
DR GO; GO:0019252; P:starch biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd03791; GT5_Glycogen_synthase_DULL1-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR NCBIfam; TIGR02095; glgA; 1.
DR PANTHER; PTHR45825; GRANULE-BOUND STARCH SYNTHASE 1, CHLOROPLASTIC/AMYLOPLASTIC; 1.
DR PANTHER; PTHR45825:SF3; GRANULE-BOUND STARCH SYNTHASE 1, CHLOROPLASTIC_AMYLOPLASTIC; 1.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Amyloplast {ECO:0000256|ARBA:ARBA00023234, ECO:0000256|RuleBase:RU361232};
KW Chloroplast {ECO:0000256|RuleBase:RU361232};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000256|RuleBase:RU361232};
KW Plastid {ECO:0000256|ARBA:ARBA00023234, ECO:0000256|RuleBase:RU361232};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Starch biosynthesis {ECO:0000256|ARBA:ARBA00022922,
KW ECO:0000256|RuleBase:RU361232};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 83..343
FT /note="Starch synthase catalytic"
FT /evidence="ECO:0000259|Pfam:PF08323"
FT DOMAIN 397..521
FT /note="Glycosyl transferase family 1"
FT /evidence="ECO:0000259|Pfam:PF00534"
SQ SEQUENCE 608 AA; 66074 MW; C31333FA87D2D8A6 CRC64;
MSTLATSQLV ATHAGLGVPD ASMFRRGGVQ GLRAAARASA AAGDALSMRT SACPAPRQQP
AARRGGRGGR FPSLVVCATA GMNVVFVGAE MAPWSKTGGL GDVLGGLPPA MAANGHRVMV
VSPRYDQYKD AWDTSVVSEI KMGDGYETVR FFHCYKRGVD RVFIDHPLFL ERVWGKTEEK
IYGPDAGTDY KDNQLRFSLL CQAALEAPRI LSLNNNPYFS GPYGEDVVFV CNDWHTGPLS
CYLKSNYQSN GIYKDAKTAF CIHNISYQGR FAFSDFPELN LPERFKSSFD FIDGYEKPVE
GRKINWMKAG ILEADRVLTV SPYYAEELIS GIARGCELDN IMRLTGITGI VNGMDVSEWD
PSKDKYIAVK YDVSTAVEAK ALNKEALQAE VGLPVDRKIP LVAFIGRLEE QKGPDVMAAA
IPLLMEEDIQ IVLLGTGKKK FERMLMSAEE KYPDKVRAVV KFNAALAHHI MAGADLLAVT
SRFEPCGLIQ LQGMRYGTPC ACASTGGLVD TIIEGKTGFH MGRLSVDCNV VEPADVKKVA
TTLKRAIKVV GTPAYEEMVK NCMIQDLSWK GPAKNWENVL LSLGVAGGEP GIEGEEIAPL
AKENVAAP
//
