GenomeNet

Database: UniProt
Entry: Q5P607_AROAE
LinkDB: Q5P607_AROAE
Original site: Q5P607_AROAE 
ID   Q5P607_AROAE            Unreviewed;       671 AA.
AC   Q5P607;
DT   04-JAN-2005, integrated into UniProtKB/TrEMBL.
DT   04-JAN-2005, sequence version 1.
DT   08-MAY-2019, entry version 102.
DE   SubName: Full=Fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase {ECO:0000313|EMBL:CAI07254.1};
GN   ORFNames=ebA2038 {ECO:0000313|EMBL:CAI07254.1};
OS   Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales;
OC   Rhodocyclaceae; Aromatoleum.
OX   NCBI_TaxID=76114 {ECO:0000313|EMBL:CAI07254.1, ECO:0000313|Proteomes:UP000006552};
RN   [1] {ECO:0000313|EMBL:CAI07254.1, ECO:0000313|Proteomes:UP000006552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EbN1 {ECO:0000313|EMBL:CAI07254.1,
RC   ECO:0000313|Proteomes:UP000006552};
RX   PubMed=15551059; DOI=10.1007/s00203-004-0742-9;
RA   Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F.,
RA   Reinhardt R.;
RT   "The genome sequence of an anaerobic aromatic-degrading denitrifying
RT   bacterium, strain EbN1.";
RL   Arch. Microbiol. 183:27-36(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a (3S)-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+)
CC         + NADH; Xref=Rhea:RHEA:22432, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57318, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945,
CC         ChEBI:CHEBI:90726; EC=1.1.1.35;
CC         Evidence={ECO:0000256|SAAS:SAAS01123908};
CC   -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC       {ECO:0000256|SAAS:SAAS00324886}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CR555306; CAI07254.1; -; Genomic_DNA.
DR   RefSeq; WP_011236975.1; NC_006513.1.
DR   STRING; 76114.ebA2038; -.
DR   EnsemblBacteria; CAI07254; CAI07254; ebA2038.
DR   KEGG; eba:ebA2038; -.
DR   eggNOG; ENOG4108SSG; Bacteria.
DR   eggNOG; COG1024; LUCA.
DR   eggNOG; COG1250; LUCA.
DR   HOGENOM; HOG000118188; -.
DR   OMA; GPYELMD; -.
DR   OrthoDB; 862072at2; -.
DR   BioCyc; AARO76114:EB_RS05695-MONOMER; -.
DR   UniPathway; UPA00659; -.
DR   Proteomes; UP000006552; Chromosome.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.10.12.10; -; 1.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR   InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   Pfam; PF00378; ECH_1; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF52096; SSF52096; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000006552};
KW   Fatty acid metabolism {ECO:0000256|SAAS:SAAS00324839};
KW   Lipid metabolism {ECO:0000256|SAAS:SAAS00324863};
KW   NAD {ECO:0000256|SAAS:SAAS00830857};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00331296};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006552}.
FT   DOMAIN       21    200       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      302    365       3HCDH. {ECO:0000259|Pfam:PF00725}.
SQ   SEQUENCE   671 AA;  72842 MW;  8084F1D54781DC87 CRC64;
     MALPFANPLL AGSSRPMPRA VAVIGAGTIG PDIGYYLKSA LPELKLTLVD VSQAALDRAL
     QRFHDYAAKA VAKGKMSEAE ARAVTANLAG TLDYGDIADA DWVLEAATEN IALKRRIFAD
     VEAVVRPDAL ITSNTSSLPA AQIFAELRHP ERATVTHFFA PAWRNPVVEV VRWEKAEPAV
     VEYLRWLFCS TGKVPLVTDD VVCFMLDRIF DNWCNESALL LERASAAEID SVAAEFVHAG
     PFFVLNLANG NPIITETNTL QAEIEGPHYR PAPVFRSVDR WLTVAPGKSV PVSPETAAAV
     RERLLGVLFS QSADILDRGI GEPADLDFGC RQALGFRKGP LDLMRDLGDD TTGRIVERFC
     AERPGMPEPR RSFAAYQAFL RHVLVDDVDG VKVITLRRPE AMNALHDEMT DEILSVIRRH
     EHDPEVTGFV ITGYGNRAFC AGADIGRFPR LLGDAAGAAQ YARDCSRLLV YLDSMKKPVV
     AALNGMVLGG GFELAIRCHG IVALQDAWMQ LPEVTLGIVH GIGAMVVPYR RWPQASSEFN
     GMLRRAERLK AARALELGVI DELAADYPGL VRAAVARVRG LSGKVAGIPS GAIDIAPLDR
     IEPKAANGQV LSAEVIRLME SAIHEAASAR TLDEALEVGY RAFGESACTH AAREGITAFQ
     EKRKPDFTKT P
//
DBGET integrated database retrieval system