ID Q5P918_AROAE Unreviewed; 843 AA.
AC Q5P918;
DT 04-JAN-2005, integrated into UniProtKB/TrEMBL.
DT 04-JAN-2005, sequence version 1.
DT 27-MAR-2024, entry version 121.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=ebA126 {ECO:0000313|EMBL:CAI06191.1};
OS Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
OC Rhodocyclaceae; Aromatoleum.
OX NCBI_TaxID=76114 {ECO:0000313|EMBL:CAI06191.1, ECO:0000313|Proteomes:UP000006552};
RN [1] {ECO:0000313|EMBL:CAI06191.1, ECO:0000313|Proteomes:UP000006552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EbN1 {ECO:0000313|EMBL:CAI06191.1,
RC ECO:0000313|Proteomes:UP000006552};
RX PubMed=15551059; DOI=10.1007/s00203-004-0742-9;
RA Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F.,
RA Reinhardt R.;
RT "The genome sequence of an anaerobic aromatic-degrading denitrifying
RT bacterium, strain EbN1.";
RL Arch. Microbiol. 183:27-36(2005).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CR555306; CAI06191.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5P918; -.
DR STRING; 76114.ebA126; -.
DR KEGG; eba:ebA126; -.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG3452; Bacteria.
DR eggNOG; COG3829; Bacteria.
DR eggNOG; COG4191; Bacteria.
DR HOGENOM; CLU_011685_0_0_4; -.
DR Proteomes; UP000006552; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 3.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CAI06191.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000006552};
KW Transferase {ECO:0000313|EMBL:CAI06191.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 226..296
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 346..391
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 422..474
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 475..513
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 618..834
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 843 AA; 94000 MW; 74B0A3CA99B373B1 CRC64;
MRLHMQGTEE FLGQLARDLA ADALDMDGFQ VRANQHIANN AELVNIVWVG PEEAVRWSAP
FDTTDWLVGD GLSGLQTQAF YRARELSRPS YGAPYANPRD KVVLEVYVPA RRGREFLGAV
VGVYSIDRMV RHLVPSWFAE KYRLALISDK GESLAVNSRV RDLDESVSYQ IPLDPPGNGL
TLRATAFRTG SQLPHALPTA MILGLSVIVL WSLWLLRTHV QRRVQVEKER DRLFNLSLDL
LCIVGLDGVF RRANPAFERI LGYAPDDLPG HPLLDLVHPD DVSDTVEQMR RLSGGEPVSL
ENRCRCVDGS FKWLAWSINP VREEKLVYAV AHDITGRKAG EDALRAESSF RKAMEESVVT
GMRAIDLDGR ITYANAAFCR MVGFEPEELI GVSRPFPYWP LEDLQLCSDN LDLTLLGRAP
PAGFEMRIRR KNGERLDARF YLSPLIDNSG TQTGWMASVT DITEPKRIRA ALEAAHERFE
AVLDGLEAAV FVADAGSDEI LFANRAFKSI HGFDAVGRTV QGVAVPQPER GDYRLDPRAL
KPADVPRELF DGELQHPLSG RWYHVRERAT RWVDGRVVRM GIATDITERK QTAEVSRQQA
ERLQRTSRLI TMGEMASTLA HELNQPLAAI ANYCMGCVTR IQSGNVRSED LLVAMQKASF
QAERAGKIIR RVREFVKKSE PRRSAVQIGE VLDDAIGFAE IDARRMSSRI VADVAAGLPA
VFADRIMIEQ VVLNLVKNGL DSMSDLPRDQ RVLVVRARAL GPSAIEVSVM DRGHGIDEDA
RARLFTPFYT TKTEGMGMGL NICRSIIEFH DGRLVVDSNP EGGTIFSFTL PTEVASEPIV
RRA
//
