ID UGPE_SALPA Reviewed; 281 AA.
AC Q5PJL0;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 04-JAN-2005, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=sn-glycerol-3-phosphate transport system permease protein UgpE {ECO:0000250|UniProtKB:P10906};
GN Name=ugpE; OrderedLocusNames=SPA3407;
OS Salmonella paratyphi A (strain ATCC 9150 / SARB42).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=295319;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 9150 / SARB42;
RX PubMed=15531882; DOI=10.1038/ng1470;
RA McClelland M., Sanderson K.E., Clifton S.W., Latreille P., Porwollik S.,
RA Sabo A., Meyer R., Bieri T., Ozersky P., McLellan M., Harkins C.R.,
RA Wang C., Nguyen C., Berghoff A., Elliott G., Kohlberg S., Strong C., Du F.,
RA Carter J., Kremizki C., Layman D., Leonard S., Sun H., Fulton L., Nash W.,
RA Miner T., Minx P., Delehaunty K., Fronick C., Magrini V., Nhan M.,
RA Warren W., Florea L., Spieth J., Wilson R.K.;
RT "Comparison of genome degradation in Paratyphi A and Typhi, human-
RT restricted serovars of Salmonella enterica that cause typhoid.";
RL Nat. Genet. 36:1268-1274(2004).
CC -!- FUNCTION: Part of the ABC transporter complex UgpBAEC involved in sn-
CC glycerol-3-phosphate (G3P) import. Probably responsible for the
CC translocation of the substrate across the membrane.
CC {ECO:0000250|UniProtKB:P10906}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (UgpC),
CC two transmembrane proteins (UgpA and UgpE) and a solute-binding protein
CC (UgpB). {ECO:0000250|UniProtKB:P10906}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000250|UniProtKB:P10906}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. UgpAE subfamily. {ECO:0000305}.
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DR EMBL; CP000026; AAV79218.1; -; Genomic_DNA.
DR RefSeq; WP_000572196.1; NC_006511.1.
DR AlphaFoldDB; Q5PJL0; -.
DR SMR; Q5PJL0; -.
DR KEGG; spt:SPA3407; -.
DR HOGENOM; CLU_016047_1_1_6; -.
DR Proteomes; UP000008185; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR43744; ABC TRANSPORTER PERMEASE PROTEIN MG189-RELATED-RELATED; 1.
DR PANTHER; PTHR43744:SF8; SN-GLYCEROL-3-PHOSPHATE TRANSPORT SYSTEM PERMEASE PROTEIN UGPE; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; MetI-like; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..281
FT /note="sn-glycerol-3-phosphate transport system permease
FT protein UgpE"
FT /id="PRO_0000292682"
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 77..268
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 281 AA; 31431 MW; 1B41B16085DE73BB CRC64;
MIENRRGLTI FSHTMLILGI AVILFPLYVA FVAATLDDRA VFETPMTLLP GTQLLENIKT
IWVNGVGVNS APFWLMMLNS FIMAFSITVG KITVSMLSAF AIVWFRFPLR NLFFWMIFIT
LMLPVEVRIF PTVEVIANLK MLDSYAGLTL PLMASATATF LFRQFFMTLP DELVEAARID
GASPMRFFRD IVLPLSKTNL AALFVITFIY GWNQYLWPLL IITDVNLGTA VAGIKGMIAT
GEGTTQWNQV MAAMLLTLIP PVVIVLAMQR AFVRGLVDSE K
//
