ID Q5PQ14_XENLA Unreviewed; 549 AA.
AC Q5PQ14;
DT 04-JAN-2005, integrated into UniProtKB/TrEMBL.
DT 04-JAN-2005, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=LOC496015 protein {ECO:0000313|EMBL:AAH87406.1};
DE SubName: Full=Myotubularin related protein 9 L homeolog {ECO:0000313|RefSeq:NP_001088751.1};
GN Name=mtmr9.L {ECO:0000313|RefSeq:NP_001088751.1,
GN ECO:0000313|Xenbase:XB-GENE-1000531};
GN Synonyms=LOC496015 {ECO:0000313|EMBL:AAH87406.1}, mtmr9
GN {ECO:0000313|RefSeq:NP_001088751.1,
GN ECO:0000313|Xenbase:XB-GENE-1000531};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH87406.1};
RN [1] {ECO:0000313|RefSeq:NP_001088751.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH87406.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis {ECO:0000313|EMBL:AAH87406.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001088751.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC087406; AAH87406.1; -; mRNA.
DR RefSeq; NP_001088751.1; NM_001095282.1.
DR IntAct; Q5PQ14; 2.
DR STRING; 8355.Q5PQ14; -.
DR PaxDb; 8355-Q5PQ14; -.
DR DNASU; 496015; -.
DR GeneID; 496015; -.
DR KEGG; xla:496015; -.
DR AGR; Xenbase:XB-GENE-1000531; -.
DR CTD; 496015; -.
DR Xenbase; XB-GENE-1000531; mtmr9.L.
DR OMA; ILKCKDF; -.
DR OrthoDB; 5474662at2759; -.
DR Proteomes; UP000186698; Chromosome 5L.
DR Bgee; 496015; Expressed in brain and 20 other cell types or tissues.
DR CDD; cd13211; PH-GRAM_MTMR9; 1.
DR CDD; cd14536; PTP-MTMR9; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR InterPro; IPR030564; Myotubularin_fam.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR PANTHER; PTHR10807:SF56; MYOTUBULARIN-RELATED PROTEIN 9; 1.
DR Pfam; PF06602; Myotub-related; 1.
DR Pfam; PF21098; PH-GRAM_MTMR6-like; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000186698}.
FT DOMAIN 123..498
FT /note="Myotubularin phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51339"
SQ SEQUENCE 549 AA; 63446 MW; 749244015A9926B8 CRC64;
MEFAELIKTP RVDNVVLHRP FHSPVWGTLC LTGHHLILSS RQDNSEELWL LHSNIDSIDK
RFVGTSGTIT IKCKDLRIIQ LEISGMEECL NIASSIEALS TLDSITLMYP FFYRPLFEVT
EDGWSLFSPE QEFEQLILET DDWRLSSVNR DYSVCLSYPQ HVMVPKSIDD DSLRKVAVFR
HAGRFPVLSY YHKKNGMVMM RSSQPLTGTN GKRCKEDEKL INATLKHGKR GYIIDTRALN
VAQQARARGG GIEQEAHYPQ WRRIHKSIER FNILQESLIK LVEACNDQSH NMDRWLSKLE
ASNWLTHIKE MLTTACLAAQ CIDREGASVL VHGSEGMDST LQVTALAQII LDPRCRTIRG
FESLIEREWL QGGHPFQQRC AQSAYSNSKH KWESPTFLLF LDCVWQILRQ FPCSFQFNER
LLLTLFEHSY ASQFGTFLGN NDYERNKLKL SQKTLSLWSW VNQPSEIKKF LNPLFEANGL
VIWPSVAPQS LQLWEGVFLR WNRSSKYLEE AYEETAHIIE YNKELQVKVN ALRRQLAELE
TEDGVLETP
//
