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Database: UniProt
Entry: Q5PQQ8
LinkDB: Q5PQQ8
Original site: Q5PQQ8 
ID   ITGBL_RAT               Reviewed;         494 AA.
AC   Q5PQQ8;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   10-APR-2019, entry version 101.
DE   RecName: Full=Integrin beta-like protein 1;
DE   Flags: Precursor;
GN   Name=Itgbl1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- DOMAIN: Contains ten tandem EGF-like repeats strikingly similar to
CC       those found in the cysteine rich 'stalk-like' structure of
CC       integrin beta-subunits.
DR   EMBL; BC087076; AAH87076.1; -; mRNA.
DR   RefSeq; NP_001017505.1; NM_001017505.1.
DR   UniGene; Rn.12893; -.
DR   ProteinModelPortal; Q5PQQ8; -.
DR   SMR; Q5PQQ8; -.
DR   STRING; 10116.ENSRNOP00000006264; -.
DR   PaxDb; Q5PQQ8; -.
DR   PRIDE; Q5PQQ8; -.
DR   Ensembl; ENSRNOT00000006264; ENSRNOP00000006264; ENSRNOG00000004516.
DR   GeneID; 498564; -.
DR   KEGG; rno:498564; -.
DR   UCSC; RGD:1560635; rat.
DR   CTD; 9358; -.
DR   RGD; 1560635; Itgbl1.
DR   eggNOG; KOG1226; Eukaryota.
DR   eggNOG; ENOG410XP60; LUCA.
DR   GeneTree; ENSGT00950000182617; -.
DR   HOGENOM; HOG000113115; -.
DR   HOVERGEN; HBG052797; -.
DR   InParanoid; Q5PQQ8; -.
DR   OMA; CQYPTHC; -.
DR   OrthoDB; 18592at2759; -.
DR   PhylomeDB; Q5PQQ8; -.
DR   TreeFam; TF332636; -.
DR   PRO; PR:Q5PQQ8; -.
DR   Proteomes; UP000002494; Chromosome 15.
DR   Bgee; ENSRNOG00000004516; Expressed in 9 organ(s), highest expression level in heart.
DR   Genevisible; Q5PQQ8; RN.
DR   GO; GO:0009986; C:cell surface; IBA:GO_Central.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005925; C:focal adhesion; IBA:GO_Central.
DR   GO; GO:0008305; C:integrin complex; IBA:GO_Central.
DR   GO; GO:0005178; F:integrin binding; IBA:GO_Central.
DR   GO; GO:0033627; P:cell adhesion mediated by integrin; IBA:GO_Central.
DR   GO; GO:0016477; P:cell migration; IBA:GO_Central.
DR   GO; GO:0007160; P:cell-matrix adhesion; IBA:GO_Central.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IBA:GO_Central.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR013111; EGF_extracell.
DR   InterPro; IPR027070; Integrin_b-like_p1.
DR   InterPro; IPR015812; Integrin_bsu.
DR   PANTHER; PTHR10082; PTHR10082; 1.
DR   PANTHER; PTHR10082:SF3; PTHR10082:SF3; 1.
DR   Pfam; PF07974; EGF_2; 4.
DR   SMART; SM00181; EGF; 6.
DR   PROSITE; PS00022; EGF_1; 5.
DR   PROSITE; PS01186; EGF_2; 5.
DR   PROSITE; PS00243; INTEGRIN_BETA; 9.
PE   2: Evidence at transcript level;
KW   Complete proteome; EGF-like domain; Glycoprotein; Reference proteome;
KW   Repeat; Secreted; Signal.
FT   SIGNAL        1     23       {ECO:0000255}.
FT   CHAIN        24    494       Integrin beta-like protein 1.
FT                                /FTId=PRO_0000323024.
FT   REPEAT       51     95       I.
FT   REPEAT       96    142       II.
FT   REPEAT      143    184       III.
FT   REPEAT      185    230       IV.
FT   REPEAT      231    275       V.
FT   REPEAT      276    326       VI.
FT   REPEAT      327    367       VII.
FT   REPEAT      368    414       VIII.
FT   REPEAT      415    454       IX.
FT   REPEAT      455    494       X.
FT   REGION       51    494       Cysteine-rich tandem repeats.
FT   COMPBIAS     63    476       Cys-rich.
FT   CARBOHYD    405    405       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
SQ   SEQUENCE   494 AA;  53904 MW;  8A60A8CA4FADD366 CRC64;
     MHPPGFKNFL LLVSSLFFIG LSAAPQSFSP SLRSLSGAPC RLSRAESERR CRAPGQPPGS
     ALCHDRGRCE CGVCICHVTE PGTYFGPLCE CHDWVCETYD GKTCAGHGTC DCGKCKCDVG
     WSGEACQYPT KCDLTKKISN QMCKNSQDVI CSNAGTCHCG RCKCDNSDGH GLIYGKFCEC
     DDRECIDDET EEICGGHGKC YCGNCYCEAG WHGDKCEFQC DITPWESKRR CTSPDGKVCS
     NRGTCVCGEC SCHDVDPTGD WGDIHGDTCE CDERDCRAVY DRYSDDFCSG HGQCNCGRCD
     CRAGWYGKKC EHPKNCPLSA EESTRKCQGS SDLPCSGRGR CECGRCTCYP PGDSRVYGKT
     CECDDRRCED LDGVVCGGRG TCSCGRCVCE KGWFGKLCQH PRKCNMTEEQ SRSLCESADG
     TLCSGKGSCH CGKCICSGEE WYISGEFCDC DDRDCDKHDG LICTGNGICS CGNCECWDGW
     NGNACEIWLG TEYP
//
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