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Database: UniProt
Entry: Q5R5X9
LinkDB: Q5R5X9
Original site: Q5R5X9 
ID   SMYD4_PONAB             Reviewed;         804 AA.
AC   Q5R5X9;
DT   21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   16-JAN-2019, entry version 60.
DE   RecName: Full=SET and MYND domain-containing protein 4;
DE            EC=2.1.1.-;
GN   Name=SMYD4;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding
CC       methyltransferase superfamily. {ECO:0000255|PROSITE-
CC       ProRule:PRU00190}.
DR   EMBL; CR860722; CAH92837.1; -; mRNA.
DR   RefSeq; NP_001127594.1; NM_001134122.1.
DR   UniGene; Pab.2543; -.
DR   ProteinModelPortal; Q5R5X9; -.
DR   SMR; Q5R5X9; -.
DR   STRING; 9601.ENSPPYP00000008770; -.
DR   PRIDE; Q5R5X9; -.
DR   GeneID; 100174673; -.
DR   KEGG; pon:100174673; -.
DR   CTD; 114826; -.
DR   eggNOG; KOG2084; Eukaryota.
DR   eggNOG; COG2940; LUCA.
DR   HOVERGEN; HBG082493; -.
DR   InParanoid; Q5R5X9; -.
DR   OrthoDB; 1278034at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 2.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR002893; Znf_MYND.
DR   Pfam; PF00856; SET; 1.
DR   Pfam; PF01753; zf-MYND; 1.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50280; SET; 1.
DR   PROSITE; PS01360; ZF_MYND_1; 1.
DR   PROSITE; PS50865; ZF_MYND_2; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome; Metal-binding; Methyltransferase;
KW   Reference proteome; S-adenosyl-L-methionine; Transferase; Zinc;
KW   Zinc-finger.
FT   CHAIN         1    804       SET and MYND domain-containing protein 4.
FT                                /FTId=PRO_0000227786.
FT   DOMAIN      233    574       SET. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00190}.
FT   ZN_FING     296    335       MYND-type. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00134}.
FT   REGION      112    114       S-adenosyl-L-methionine binding.
FT                                {ECO:0000250}.
FT   REGION      539    540       S-adenosyl-L-methionine binding.
FT                                {ECO:0000250}.
FT   BINDING     427    427       S-adenosyl-L-methionine.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00190}.
FT   BINDING     573    573       S-adenosyl-L-methionine.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00190}.
FT   BINDING     595    595       S-adenosyl-L-methionine.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00190}.
SQ   SEQUENCE   804 AA;  89276 MW;  DDC4C455AF3D9F51 CRC64;
     MDLPVDEWKS YLLQKWASLP TSVQVTISTA ETLRDIFLHS SSLLQPEDEL FLKRLSKGYL
     VGKDLDAPLF YREEGNKKFQ EKDYTGAAVL YSKGVSHSRP NTEDMSLCYA NRSAALFHLG
     EYETCLKDIN RAQTHGYPER LQPKIMLRKA ECLVALGRLQ EASQTISDLE RNFTATPTLA
     NVRPQTLQRN LHHLKMKVQE KDKLTETFPA ALAKTLEDAA LREENEQLSS ASSSVGLCID
     PLKGRYLVAT KDILPGELLV KEDAFVSVLN PGELPPPHHG LDSKWDTRVT NGDLYCHRCL
     KHTLATVPCD GCSYAKYCSQ ECLQQAWELY HRTECPLGGL LLTLGVFCHI ALRLTLLVGF
     EDVRKIITKV CDKISNKDIC LPESNNQVKT LNYGLGESEK SGNIIETPIP GCDINGKYEN
     NYNAVFNLLP HTENHSPEHK FLCALCVSAL CRQLEAASFQ AIPTERSVNS SQLQAAVTPE
     LCPDVTIWGV AMLRHMLQLQ CNAQAMTTIQ HTGSKGSIVT DSRQVRLATG IFPVVSLLNH
     SCSPNTSMSF ISTVATIQAS QRIRKGQEIL HCYGPHKSRM GVAERQQELR SQYFFDCACP
     ACQTEAHRMA AEPRWEAFCC NSCGAPMQGD DVLHCGSRSC AESAVSRDHL VSRLQDLQQQ
     VGVAQKLLRD GELERAVQQL LGCQRDAESF LWAEHALVGE IADGLARACA ALGDWQKAAT
     HLQRSLRVVE VRHGPSSVEM GHELFKLAQI FFNGFAVPEA LSTIQKAEEA LLLHCGPWDD
     EIQELQKMKS CLLDLPPTPV GPAV
//
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