ID Q5SX60_MOUSE Unreviewed; 80 AA.
AC Q5SX60;
DT 21-DEC-2004, integrated into UniProtKB/TrEMBL.
DT 21-DEC-2004, sequence version 1.
DT 27-MAR-2024, entry version 113.
DE RecName: Full=Enolase 3 {ECO:0000256|ARBA:ARBA00041942};
DE AltName: Full=Muscle-specific enolase {ECO:0000256|ARBA:ARBA00042698};
DE AltName: Full=Skeletal muscle enolase {ECO:0000256|ARBA:ARBA00042657};
DE Flags: Fragment;
GN Name=Eno3 {ECO:0000313|Ensembl:ENSMUSP00000121640.2,
GN ECO:0000313|MGI:MGI:95395};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000121640.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000121640.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121640.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000121640.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121640.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Glycolytic enzyme that catalyzes the conversion of 2-
CC phosphoglycerate to phosphoenolpyruvate. Appears to have a function in
CC striated muscle development and regeneration.
CC {ECO:0000256|ARBA:ARBA00037209}.
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DR AlphaFoldDB; Q5SX60; -.
DR SMR; Q5SX60; -.
DR jPOST; Q5SX60; -.
DR MaxQB; Q5SX60; -.
DR PeptideAtlas; Q5SX60; -.
DR ProteomicsDB; 347484; -.
DR Antibodypedia; 630; 480 antibodies from 34 providers.
DR Ensembl; ENSMUST00000134087.8; ENSMUSP00000121640.2; ENSMUSG00000060600.16.
DR AGR; MGI:95395; -.
DR MGI; MGI:95395; Eno3.
DR VEuPathDB; HostDB:ENSMUSG00000060600; -.
DR GeneTree; ENSGT00950000182805; -.
DR OMA; RHIADIS; -.
DR Proteomes; UP000000589; Chromosome 11.
DR Bgee; ENSMUSG00000060600; Expressed in sternocleidomastoid and 260 other cell types or tissues.
DR ExpressionAtlas; Q5SX60; baseline and differential.
DR GO; GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004634; F:phosphopyruvate hydratase activity; IEA:InterPro.
DR GO; GO:0006096; P:glycolytic process; IEA:InterPro.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR000941; Enolase.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR020811; Enolase_N.
DR PANTHER; PTHR11902:SF5; BETA-ENOLASE; 1.
DR PANTHER; PTHR11902; ENOLASE; 1.
DR Pfam; PF03952; Enolase_N; 1.
DR SMART; SM01193; Enolase_N; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:Q5SX60,
KW ECO:0007829|MaxQB:Q5SX60};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 3..78
FT /note="Enolase N-terminal"
FT /evidence="ECO:0000259|SMART:SM01193"
FT NON_TER 80
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000121640.2"
SQ SEQUENCE 80 AA; 8692 MW; 7BCAD76457555C2D CRC64;
MAMQKIFARE ILDSRGNPTV EVDLHTAKGR FRAAVPSGAS TGIYEALELR DGDKARYLGK
GVLKAVEHIN KTLGPALLEK
//
