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Database: UniProt
Entry: Q5TQ03_ANOGA
LinkDB: Q5TQ03_ANOGA
Original site: Q5TQ03_ANOGA 
ID   Q5TQ03_ANOGA            Unreviewed;       926 AA.
AC   Q5TQ03;
DT   07-DEC-2004, integrated into UniProtKB/TrEMBL.
DT   23-OCT-2007, sequence version 3.
DT   23-MAY-2018, entry version 99.
DE   SubName: Full=AGAP011459-PA {ECO:0000313|EMBL:EAL39479.3};
DE   Flags: Fragment;
GN   Name=3291342 {ECO:0000313|VectorBase:AGAP011459-PA};
GN   ORFNames=AgaP_AGAP011459 {ECO:0000313|EMBL:EAL39479.3};
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Anophelinae; Anopheles.
OX   NCBI_TaxID=7165 {ECO:0000313|EMBL:EAL39479.3, ECO:0000313|Proteomes:UP000007062};
RN   [1] {ECO:0000313|EMBL:EAL39479.3, ECO:0000313|Proteomes:UP000007062, ECO:0000313|VectorBase:AGAP011459-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST {ECO:0000313|EMBL:EAL39479.3,
RC   ECO:0000313|Proteomes:UP000007062};
RX   PubMed=12364791; DOI=10.1126/science.1076181;
RA   Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA   Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA   Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B.,
RA   Lai Z., Kraft C.L., Abril J.F., Anthouard V., Arensburger P.,
RA   Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V.,
RA   Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S.,
RA   Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M.,
RA   Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I.,
RA   Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z.,
RA   Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R.,
RA   Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E.,
RA   Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F.,
RA   Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R.,
RA   Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C.,
RA   Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V.,
RA   Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D.,
RA   Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H.,
RA   Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A.,
RA   Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA   Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F.,
RA   Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S.,
RA   Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C.,
RA   Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.;
RT   "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL   Science 298:129-149(2002).
RN   [2] {ECO:0000313|EMBL:EAL39479.3}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EAL39479.3};
RG   The Anopheles Genome Sequencing Consortium;
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:EAL39479.3}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EAL39479.3};
RX   PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA   Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT   "The Anopheles gambiae genome: an update.";
RL   Trends Parasitol. 20:49-52(2004).
RN   [4] {ECO:0000313|EMBL:EAL39479.3}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EAL39479.3};
RX   PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA   Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA   Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT   "Update of the Anopheles gambiae PEST genome assembly.";
RL   Genome Biol. 8:R5-R5(2007).
RN   [5] {ECO:0000313|EMBL:EAL39479.3}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EAL39479.3};
RG   VectorBase;
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|VectorBase:AGAP011459-PA}
RP   IDENTIFICATION.
RC   STRAIN=PEST {ECO:0000313|VectorBase:AGAP011459-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; AAAB01008966; EAL39479.3; -; Genomic_DNA.
DR   RefSeq; XP_554755.3; XM_554755.3.
DR   ProteinModelPortal; Q5TQ03; -.
DR   STRING; 7165.AGAP011459-PA; -.
DR   EnsemblMetazoa; AGAP011459-RA; AGAP011459-PA; AGAP011459.
DR   GeneID; 3291342; -.
DR   KEGG; aga:AgaP_AGAP011459; -.
DR   VectorBase; AGAP011459-RA; AGAP011459-PA; AGAP011459.
DR   eggNOG; KOG0499; Eukaryota.
DR   eggNOG; ENOG410ZJ5U; LUCA.
DR   HOGENOM; HOG000045560; -.
DR   InParanoid; Q5TQ03; -.
DR   KO; K04952; -.
DR   OMA; IAYYPNA; -.
DR   OrthoDB; EOG091G03EW; -.
DR   PhylomeDB; Q5TQ03; -.
DR   Proteomes; UP000007062; Chromosome 3L.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:GO_Central.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:GO_Central.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   PROSITE; PS00888; CNMP_BINDING_1; 1.
DR   PROSITE; PS00889; CNMP_BINDING_2; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007062};
KW   Ion transport {ECO:0000256|SAAS:SAAS00502700};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007062};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00137614,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00137754,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00502637}.
FT   TRANSMEM    345    364       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    485    503       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    549    570       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      653    759       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
FT   COILED       31     51       {ECO:0000256|SAM:Coils}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:EAL39479.3}.
SQ   SEQUENCE   926 AA;  105208 MW;  F7F3E8B0A94D65C7 CRC64;
     EVKLHKSLEE ISKDIRELED FISVTEDILR REREEDEQLT LRERKRKAAE QVNITQKRRI
     KSFSPKGGGG GYKSKLYFRN GKIGCQEAEN AVSNLRSTHE LVKRIINDES NMLVKLEHQH
     YTTAEQDGLE SRSSSADTPV ESLQMCVTES AGTSLCEDEV PAAGLAPSQP LALQQETVSM
     VPGGDSSGLN GEERQRHVDD GEHIESANGI SMEPMEDRRN SEAFNDFIEA LRRIPLTNSC
     PSETMPTSGN DFVTVRLRHL ANRFSERTRK MRRKLEIPPT PSSSASAPST APSMQKHSVN
     QRTIQNSALT LQSATETPGC SHYLFCPIFC CGGRSDNVLD PQGKFYIAWL FIVSLSFLYN
     AWVIPLRSSF PYQTPENTKY WIAMDICADV IYLLDILFVK HRLMYLYEGF WVKDKNLTRK
     NYMRKLQFKM DLLALVPLDL LYLRFGTEHV VFRAPRLLKI QSFWEFFKLI DRVISSPHII
     RVVKTLTYML YMIHLTACAY YAYSAYQGLG SNRWVFNNKG HAYVRCFAFA TKTATSIGKN
     PKPEKEGELM FMTAAWLMGV FVFALLIGQI RDIIATATRS KSEYKQLVDE TLEYMRRLNL
     PTDLQRRVKM WFTFTWEQQK CLDETHIMDA LPANLKTDIA ISVHIQTLSK VQLFADCEEA
     LLRELVLKLR SVTFLPGDFV CRKGEVGKEM YIVKTGQVQV MGGPRNDVVL ATLYEGSVFG
     EISLLAINGA EGNRRTADVR SKGFSNLFVL SKSDLNEAIV YYPNAQAILK KRAKSLMRKN
     AAREKAESQQ SIDTKGSEVD VVIRNPPDPA SPKLLKTVIQ ALPQESAAVQ LLMQGFKMVE
     APVEEPEPEG PQSPEVGGER VVEVRHTTEV QIENEKNFEL PCDLVYSIKK ELMENNSYIN
     LTDAEKYKLL HELSKDEYED QEKSPV
//
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