ID Q5TSX3_ANOGA Unreviewed; 2046 AA.
AC Q5TSX3;
DT 07-DEC-2004, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 4.
DT 27-MAR-2024, entry version 113.
DE SubName: Full=AGAP004507-PA {ECO:0000313|EMBL:EAL40554.4};
DE Flags: Fragment;
GN ORFNames=AgaP_AGAP004507 {ECO:0000313|EMBL:EAL40554.4};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAL40554.4};
RN [1] {ECO:0000313|EMBL:EAL40554.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAL40554.4};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAL40554.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAL40554.4};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAL40554.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAL40554.4};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAL40554.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAL40554.4};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAL40554.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAL40554.4};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC ProRule:PRU00983}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL40554.4}.
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DR EMBL; AAAB01008898; EAL40554.4; -; Genomic_DNA.
DR RefSeq; XP_562267.4; XM_562267.4.
DR GeneID; 1274653; -.
DR VEuPathDB; VectorBase:AGAP004507; -.
DR OMA; MRDFGHS; -.
DR OrthoDB; 8258at2759; -.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd08695; C2_Dock-B; 1.
DR Gene3D; 1.20.58.740; -; 1.
DR Gene3D; 1.25.40.410; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.20.1270.350; Dedicator of cytokinesis N-terminal subdomain; 1.
DR InterPro; IPR037811; C2_Dock-B.
DR InterPro; IPR027007; C2_DOCK-type_domain.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR026791; DOCK.
DR InterPro; IPR043161; DOCK_C_lobe_A.
DR InterPro; IPR043162; DOCK_C_lobe_C.
DR InterPro; IPR032376; DOCK_N.
DR InterPro; IPR042455; DOCK_N_sub1.
DR InterPro; IPR027357; DOCKER_dom.
DR InterPro; IPR046769; DOCKER_Lobe_A.
DR InterPro; IPR046770; DOCKER_Lobe_B.
DR InterPro; IPR046773; DOCKER_Lobe_C.
DR PANTHER; PTHR45653; DEDICATOR OF CYTOKINESIS; 1.
DR PANTHER; PTHR45653:SF12; SPONGE, ISOFORM E; 1.
DR Pfam; PF06920; DHR-2_Lobe_A; 1.
DR Pfam; PF20422; DHR-2_Lobe_B; 1.
DR Pfam; PF20421; DHR-2_Lobe_C; 1.
DR Pfam; PF14429; DOCK-C2; 1.
DR Pfam; PF16172; DOCK_N; 1.
DR PROSITE; PS51650; C2_DOCK; 1.
DR PROSITE; PS51651; DOCKER; 1.
PE 3: Inferred from homology;
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EAL40554.4"
SQ SEQUENCE 2046 AA; 230154 MW; F987021A8CC973F3 CRC64;
DLSKVDPVVA ECTLVLREWS EIWKRLFVRE EYKFTSLRKV MLALLESRRE LLSSTLTQDQ
TYDLQMKVIS KIDWGNRKLG LDLVPRSGTL AVDPQKIGIV SLHQVHVNSA ENAKAASNRG
TLRRKAGKKI HTHHLYFCMR DFGHRIGDDA EIYFYLYDGN TNRMRALSER FLVRIARDGF
STYVETSHNC TIFTDLGSSD LNQDLYLIAN VMRVGKMLHS ESVKKGDKLT TTTHAYRRPY
GVGVLPLNEI AQFDYSVESE EKEFSFKIFQ CEEKDYHQLH ELIIKKASGK FQPINASTQS
HYGLVVSMKL LHGEIGQAKL EQPILFQGTA ITKKIGFPDV IMPGDVRNDL FLTLERGEFE
RVGISTAKNI EITALVLDEN GRMVQECIAI ASGSPLQAYY KSMVLYHNNS PAWNETIRMF
VPIDKFSKAH VRFEFRSCST RDKSDPKLFG FSFARLMEPG GATIADGAHE LYVYKCEDAL
KVQPNVYLRL PCSAGDRQAQ GDSPSPYHRS SKEAFYVRTI LCSTKLTQNG DLLSLLQWRN
RPEGIQDSLQ RVLRLHNEEL IKFLQDVLDA LFALFSTDDG NSTPHSGLVF HVLVNIFSLM
QSSKFQHFKP VMDAYIRNHF AAPLVYQGLL SSVQHLADWL TTTDNLEPIV QCFSSLEFIF
KLIIQSRKLF AHASGGQYED KFKNDLFSVF LSLNGMLAVP STTQILATQE ALLSNAGVVF
EQLRTIITRP ELETLVKSML DAVPKDAQPP LIQAKLKSIK DMVSGQLFED DELRSVILNI
ACKHLRIHLA RRDELRLCSE ILAEVLIKLY EAKAKSGEKP SNAIHHDLDT LFANIFPILL
QTINVLSNGG NENLVCSLFA VKLGLLQLLD ESHYQRMWDR QQTGISPTGG GSVVGGKELK
DFIQQCLAIF KDILEQDWMI FSKDWLVMKM AANDVLRRTL EELAKPLVYR FLGPQSFDSQ
LWWSYFSVAV IFLTQPSLQI EQYHETKRRK LLSTHGDMRV MMGFQILSMW AQLGEHKLHF
IPSMVGPFLE VTLVPEPALR KATFTVFYDM MQCEQVSRGS FRLVESELID KLDLLISENK
GDDEYRELFS TILLERVQTE NPSWRESGIA FISSVTRLLE RLLDYRSVMQ GDENRDKRMT
CTVNLLNFYN DEINRKEMYV RYIYKLLDLH LGAENYVEAG LTLKLYADML SWDSENISDE
SNGPREWEQK EKIYKNIISY FDKGKCWEKG IPLCKELAIF YERKRFDYNR LSDALVQEAK
FFQNILTQLR PEPEYFRVGY YGTGFPSFVR NKQFIYRGLE YERIGAFIQR LQTEFPTAFI
LDKKQYPPDS SILNSLEQRF HVVNVRPIAD PYHLKSAKVT VPEKISKYYE VNDVTRFQYD
RPVHKGTVDK DNEFKSLWIV RTIYETAQPL PGILRWFEVS KTSEHELTPV EFACETIANV
NKELSDLIVQ YRLDPKRNLN PFTMRLQGSV DANVNGGFSK YQDAFFSERF AKSAEGRDQS
VHVQRLKRLI FEQMQILRQA LELHRSLAPE QVLPLHNRLS EAFLELEKST SEWKTNINIP
TKPLPPLPIG QQQQPHGGGG TDLYGGGTGA NGGKMGLSNG GAQELAYFPE DYDGTYMSVN
KKTLSLSGIV PMTALTSSPA PHIPPRDSTG AVMLPAVCSP TAPPLPPRGH TPDKRSSNPM
PFTEYVEQQQ QQLQQHSSLP GKNRQKKYSL YEISLNDSGN YGSPRNLAEF RQGFYRDSGI
STSTQELNNL NAASSSGATG GGPLPQGGEG CAQTPPHQHY HQPMTITSAA TTSHDDYNII
ANGNTLPVMS QHPVRGHQKT NSNPEAYQSI PMVAGTTAPS TGGTSVQPPP PPIPPKSASL
HHQHSLPVGS LGGGGLANNN INNNNNNHSN NNSTLSFHSQ GAHAQHLPPP SHYHHQRNQS
LNLSTNSSSD GEQLSLNDIS PAPPPMFNDN FSDSFSDECD NPAPSCGSVP ISQHAKMTPS
PGRSVGGGGS GAAGAGVVVT PGGYNSSTLN GSASSGEALE LSSITTTTTT TTIISLRRDD
EDEIFY
//
