ID Q5TTL0_ANOGA Unreviewed; 359 AA.
AC Q5TTL0;
DT 07-DEC-2004, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 2.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=AGAP003064-PA {ECO:0000313|EMBL:EAL40694.2};
GN Name=4577001 {ECO:0000313|EnsemblMetazoa:AGAP003064-PA};
GN ORFNames=AgaP_AGAP003064 {ECO:0000313|EMBL:EAL40694.2};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAL40694.2};
RN [1] {ECO:0000313|EMBL:EAL40694.2, ECO:0000313|Proteomes:UP000007062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAL40694.2,
RC ECO:0000313|Proteomes:UP000007062};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAL40694.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAL40694.2};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAL40694.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAL40694.2};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAL40694.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAL40694.2};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAL40694.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAL40694.2};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EnsemblMetazoa:AGAP003064-PA}
RP IDENTIFICATION.
RC STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP003064-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AAAB01008879; EAL40694.2; -; Genomic_DNA.
DR RefSeq; XP_562821.2; XM_562821.3.
DR AlphaFoldDB; Q5TTL0; -.
DR STRING; 7165.Q5TTL0; -.
DR PaxDb; 7165-AGAP003064-PA; -.
DR EnsemblMetazoa; AGAP003064-RA; AGAP003064-PA; AGAP003064.
DR GeneID; 4577001; -.
DR KEGG; aga:AgaP_AGAP003064; -.
DR VEuPathDB; VectorBase:AGAP003064; -.
DR eggNOG; KOG1667; Eukaryota.
DR HOGENOM; CLU_040079_0_0_1; -.
DR InParanoid; Q5TTL0; -.
DR OMA; KHRWVAK; -.
DR OrthoDB; 1360344at2759; -.
DR Proteomes; UP000007062; Chromosome 2R.
DR GO; GO:0008270; F:zinc ion binding; IBA:GO_Central.
DR GO; GO:0051298; P:centrosome duplication; IBA:GO_Central.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 4.10.1130.20; -; 2.
DR InterPro; IPR007051; CHORD_dom.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR PANTHER; PTHR46983:SF3; CHPADIPLOID STATE MAINTENANCE PROTEIN CHPA; 1.
DR PANTHER; PTHR46983; CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF04968; CHORD; 2.
DR Pfam; PF04969; CS; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR PROSITE; PS51401; CHORD; 2.
DR PROSITE; PS51203; CS; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007062};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 6..64
FT /note="CHORD"
FT /evidence="ECO:0000259|PROSITE:PS51401"
FT DOMAIN 149..208
FT /note="CHORD"
FT /evidence="ECO:0000259|PROSITE:PS51401"
FT DOMAIN 219..310
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT REGION 61..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 310..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..86
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..336
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 359 AA; 40472 MW; 094D61B541B50C84 CRC64;
MTKVVCYNRG CGQSFDPQNN TEDCVHHPGV PFFHDAYKGW TCCNKKSVDF TEFLNIKGCT
QGLHSNEKPP EPEKRKEDTV LAEEPAPTEV KIREPIRPSM ERPPFETALT SLDPWVAPAF
RKQIDEMPQT AVKRKSPTDA AAIEAGTVCK HGGCSCTYED AKTSDKPCVY HPGVPIFHEG
MKFWSCCQRK TSDFTAFMNQ AGCETGKHLW VSEEDESKAI KCRLDWHQTA TTVVVTVYAK
NYHYAKSYVR VNPIRLAICL VFPQQDGNQY NVDMELRGVI DVTQCKVQMF GTKVEITLIK
AEPGTWAKLD FPREKKAEQQ KEDANKQAST KNGDDSDSDV DLDDLEPTMR TATITEIKD
//
