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Database: UniProt
Entry: Q5UQ96
LinkDB: Q5UQ96
Original site: Q5UQ96 
ID   YL540_MIMIV             Reviewed;         695 AA.
AC   Q5UQ96;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   18-SEP-2019, entry version 67.
DE   RecName: Full=Putative ATP-dependent RNA helicase L540;
DE            EC=3.6.4.13;
GN   OrderedLocusNames=MIMI_L540;
OS   Acanthamoeba polyphaga mimivirus (APMV).
OC   Viruses; Mimiviridae; Mimivirus.
OX   NCBI_TaxID=212035;
OH   NCBI_TaxID=5757; Acanthamoeba polyphaga (Amoeba).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rowbotham-Bradford;
RX   PubMed=15486256; DOI=10.1126/science.1101485;
RA   Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H.,
RA   La Scola B., Susan M., Claverie J.-M.;
RT   "The 1.2-megabase genome sequence of Mimivirus.";
RL   Science 306:1344-1350(2004).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], AND
RP   SUBCELLULAR LOCATION.
RX   PubMed=16971431; DOI=10.1128/jvi.00940-06;
RA   Renesto P., Abergel C., Decloquement P., Moinier D., Azza S.,
RA   Ogata H., Fourquet P., Gorvel J.-P., Claverie J.-M., Raoult D.;
RT   "Mimivirus giant particles incorporate a large fraction of anonymous
RT   and unique gene products.";
RL   J. Virol. 80:11678-11685(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:16971431}.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH
CC       subfamily. {ECO:0000305}.
DR   EMBL; AY653733; AAV50804.1; -; Genomic_DNA.
DR   RefSeq; YP_003987055.1; NC_014649.1.
DR   SMR; Q5UQ96; -.
DR   PRIDE; Q5UQ96; -.
DR   GeneID; 9925174; -.
DR   KEGG; vg:9925174; -.
DR   OrthoDB; 1812at10239; -.
DR   Proteomes; UP000001134; Genome.
DR   GO; GO:0019012; C:virion; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF04408; HA2; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Complete proteome; Helicase; Hydrolase;
KW   Nucleotide-binding; Reference proteome; Virion.
FT   CHAIN         1    695       Putative ATP-dependent RNA helicase L540.
FT                                /FTId=PRO_0000247281.
FT   DOMAIN       53    219       Helicase ATP-binding.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00541}.
FT   DOMAIN      247    434       Helicase C-terminal.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00542}.
FT   NP_BIND      66     73       ATP. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
FT   MOTIF       164    167       DEAH box.
SQ   SEQUENCE   695 AA;  79556 MW;  12A49B7C1F544616 CRC64;
     MASNLTFEDK IGILDPKGLR PNPLNNEPYS DDYKKLAMVW STYPAYSAAD RVLSALENYQ
     LVFVTSSTGS GKSVLIPKLA LHYTNYNGRV VMTLPKRIIT LSAAIFSAKV SDVKLGESIG
     YAYKGSDKSM YNDQNKIIYV TDGIFVMEYV RDPLLSKFNV VIIDEAHERR IQIDLILLFL
     RTLLQSGNRP DLKVIIMSAT IDTDKYQKYF NSVDSTVIDI AGQPNHPIET HFMDKPVTSY
     MKEGLELIED LIHQQIKKDM LFFITTSNEA LQLCRSIRPQ YPRVYCVEVY SDMDKNLKQY
     AESRDKYLEL GNYDQKLVMA TNVAESSLTI DGLVYVIDSG YELSSRFDPE CYGQILEKKF
     VSKAQALQRR GRVGRTEPGV CYHLLTKQQF DGLADYPTPD ILRQDITMDL IKIIQVSPNK
     TYAEGINMMN QLMDPPLRSH INATRNLFDL YNVVDDNGIL TQVGIVATQF SSLPLNRILF
     LIYAFELQCA REASIIVAMT EFLNGRVTNL FYKSDTICES NCEKQAANLL LEKLIQKRGD
     HFTYLKIYQE FSKSTDQKSW ARKYGVRLDT INNIERTANQ YFYRILNLLR KPRLPNNKNT
     LIDTSIDTPM DIQSRISSTD TKTNLLNALK KSHQHLTASK LKPTYSKENI TGKISRDSVL
     NQIYKKNEIS KKKIIYDELS NINGKWEFRT VTIIS
//
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