ID Q5W125_HUMAN Unreviewed; 203 AA.
AC Q5W125;
DT 07-DEC-2004, integrated into UniProtKB/TrEMBL.
DT 07-DEC-2004, sequence version 1.
DT 27-MAR-2024, entry version 117.
DE SubName: Full=Nicotinamide riboside kinase 1 {ECO:0000313|Ensembl:ENSP00000366007.1};
GN Name=NMRK1 {ECO:0000313|Ensembl:ENSP00000366007.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000366007.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000366007.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15164053; DOI=10.1038/nature02465;
RA Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L.,
RA Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R.,
RA Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S.,
RA Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K.,
RA Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y.,
RA Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C.,
RA Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E.,
RA Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M.,
RA Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J.,
RA Frankish A., Frankland J.A., French L., Fricker D.G., Garner P.,
RA Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
RA Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
RA Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
RA Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
RA Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
RA Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S.,
RA Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J.,
RA Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E.,
RA McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V.,
RA Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S.,
RA Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K.,
RA Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J.,
RA Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M.,
RA West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L.,
RA Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.,
RA Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J.,
RA Dunham I.;
RT "DNA sequence and analysis of human chromosome 9.";
RL Nature 429:369-374(2004).
RN [2] {ECO:0007829|PubMed:24275569}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L.,
RA Ye M., Zou H.;
RT "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver
RT phosphoproteome.";
RL J. Proteomics 96:253-262(2014).
RN [3] {ECO:0000313|Ensembl:ENSP00000366007.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AL133548; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001317607.1; NM_001330678.1.
DR RefSeq; NP_001317608.1; NM_001330679.1.
DR RefSeq; XP_011517119.1; XM_011518817.1.
DR RefSeq; XP_011517120.1; XM_011518818.1.
DR RefSeq; XP_016870357.1; XM_017014868.1.
DR RefSeq; XP_016870358.1; XM_017014869.1.
DR AlphaFoldDB; Q5W125; -.
DR SMR; Q5W125; -.
DR MassIVE; Q5W125; -.
DR MaxQB; Q5W125; -.
DR PeptideAtlas; Q5W125; -.
DR ProteomicsDB; 65793; -.
DR Antibodypedia; 27143; 188 antibodies from 23 providers.
DR DNASU; 54981; -.
DR Ensembl; ENST00000376811.5; ENSP00000366007.1; ENSG00000106733.21.
DR GeneID; 54981; -.
DR UCSC; uc004ajs.5; human.
DR CTD; 54981; -.
DR HGNC; HGNC:26057; NMRK1.
DR VEuPathDB; HostDB:ENSG00000106733; -.
DR GeneTree; ENSGT00940000159384; -.
DR OrthoDB; 5391879at2759; -.
DR PhylomeDB; Q5W125; -.
DR BioGRID-ORCS; 54981; 10 hits in 1151 CRISPR screens.
DR ChiTaRS; NMRK1; human.
DR GenomeRNAi; 54981; -.
DR Proteomes; UP000005640; Chromosome 9.
DR Bgee; ENSG00000106733; Expressed in cervix squamous epithelium and 201 other cell types or tissues.
DR ExpressionAtlas; Q5W125; baseline and differential.
DR CDD; cd02024; NRK1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10285:SF126; NICOTINAMIDE RIBOSIDE KINASE 1; 1.
DR PANTHER; PTHR10285; URIDINE KINASE; 1.
DR Pfam; PF13238; AAA_18; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:Q5W125,
KW ECO:0007829|MaxQB:Q5W125};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
SQ SEQUENCE 203 AA; 23797 MW; CCD154003AFF71F8 CRC64;
MGKRRHRRGN VISCVTNSGK TTLAKNLQKH LPNCSVISQD DFFKPESEIE TDKNGFLQYD
VLEALNMEKM MSAISCWMES ARHSVVSTDQ ESAEEIPILI IEGFLLFNYK PLDTIWNRSY
FLTIPYEECK RRRSTRVYQP PDSPGYFDGH VWPMYLKYRQ EMQDITWEVV YLDGTKSEED
LFLQVYEDLI QELAKQKCLQ VTA
//
