ID Q5XGM0_XENLA Unreviewed; 448 AA.
AC Q5XGM0;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=Bifunctional apoptosis regulator L homeolog {ECO:0000313|RefSeq:NP_001088347.1};
DE SubName: Full=LOC495189 protein {ECO:0000313|EMBL:AAH84417.1};
GN Name=bfar.L {ECO:0000313|RefSeq:NP_001088347.1,
GN ECO:0000313|Xenbase:XB-GENE-979529};
GN Synonyms=bfar {ECO:0000313|RefSeq:NP_001088347.1,
GN ECO:0000313|Xenbase:XB-GENE-979529}, LOC495189
GN {ECO:0000313|EMBL:AAH84417.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH84417.1};
RN [1] {ECO:0000313|RefSeq:NP_001088347.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH84417.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney {ECO:0000313|EMBL:AAH84417.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001088347.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; BC084417; AAH84417.1; -; mRNA.
DR RefSeq; NP_001088347.1; NM_001094878.1.
DR DNASU; 495189; -.
DR GeneID; 495189; -.
DR KEGG; xla:495189; -.
DR AGR; Xenbase:XB-GENE-979529; -.
DR CTD; 495189; -.
DR Xenbase; XB-GENE-979529; bfar.L.
DR OrthoDB; 4047619at2759; -.
DR Proteomes; UP000186698; Chromosome 9_10L.
DR Bgee; 495189; Expressed in egg cell and 19 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16497; RING-HC_BAR; 1.
DR CDD; cd09513; SAM_BAR; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR15898:SF21; BIFUNCTIONAL APOPTOSIS REGULATOR; 1.
DR PANTHER; PTHR15898; UNCHARACTERIZED; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..71
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 178..245
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
SQ SEQUENCE 448 AA; 52499 MW; 7F09F2A09CAED4CA CRC64;
MEEDVKLDGN EGTRIATAKL DRKISVSEFS CHCCYDILVN PTTLNCGHSF CRHCLALWWV
SSKKTECPEC RNTWEGFPKV NILLRDIIEK LFPDAIQQKY KDVEGSHEII HALQAFNKYG
SDQNQASAGT QGNQPRGGGF FSGVLTALTS VAVVLLVYHW SSRDSEQDLL VHKPVAKWTA
EEVVLWLEQL GPWASHYKEH FLSGNVNGRL LLTLAEEEFS KNPYSIENSS HRKAILLELD
RVKTLGVKPP QNLWEYKAVN PGKSLFLLYA LKSSPRLSML YLYLFDYAET FLPFIHTTCP
LQEEQKEQEE DLFAKFIDLQ DPTWRQWREF LVKYVFLPYQ LIAEFAWDWL ELHYWTSRFI
IVNAMLLTVL ELFSFWNLWS RRELKNLPQL MWRHFWNMST HGICVAIFWP VIPQFVCNCF
FYWALYFNPI INIDLVVKEI RRFETQVV
//
