ID Q5YMN5_NOCFA Unreviewed; 748 AA.
AC Q5YMN5;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Putative membrane protein {ECO:0000313|EMBL:BAD60556.1};
GN OrderedLocusNames=PNF1_310 {ECO:0000313|EMBL:BAD60556.1};
OS Nocardia farcinica (strain IFM 10152).
OG Plasmid pNF1 {ECO:0000313|EMBL:BAD60556.1,
OG ECO:0000313|Proteomes:UP000006820}.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=247156 {ECO:0000313|EMBL:BAD60556.1, ECO:0000313|Proteomes:UP000006820};
RN [1] {ECO:0000313|EMBL:BAD60556.1, ECO:0000313|Proteomes:UP000006820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 10152 {ECO:0000313|EMBL:BAD60556.1,
RC ECO:0000313|Proteomes:UP000006820};
RC PLASMID=Plasmid pNF1 {ECO:0000313|Proteomes:UP000006820};
RX PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA Shiba T., Hattori M.;
RT "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AP006619; BAD60556.1; -; Genomic_DNA.
DR RefSeq; WP_011212238.1; NC_006362.1.
DR AlphaFoldDB; Q5YMN5; -.
DR GeneID; 61136266; -.
DR KEGG; nfa:PNF1_310; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_5_2_11; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000006820; Plasmid pNF1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Plasmid {ECO:0000313|EMBL:BAD60556.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006820};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 39..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 559..578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 590..610
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 622..642
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 700..719
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 237..361
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 748 AA; 78189 MW; F254E0EF2EC593FB CRC64;
MNQQQQSAVT ERSPQQPLPP DSPGLLYRWG VLMARRRRTA LAIWGVLLAV CAVAYPLLEN
RLGAMDFGVE GSESTEVDRL VAQHFPQFGA EQAVIVLQSG ALTATDSDFR AVVARTVTAA
EEVQGVVDVV GPYDGLPGSQ ISADGHVAIA LAGMDGDMAE RARVARDLQD AIASTGDDSI
DVGLTGYSAV QNAATELQNA DLARAEAIGI PVALILLVLA LGALAAAAVP IGVAIAGLLT
AVGVLFTLTT VTAFDSLTVA MATMVGLGVG IDYAMFIVSR FREELAHHTV ADHAAIAAAV
GRSLATAGKT ILVSGLVVMI SLCALIIIQA PIFRGIAIGV ATAVTSMLIV AVTLLPALLA
ALGPAINRGA LPARWRPADS TANAPGALSG RWARWAYLVM RRPVLFGTAA VAVLVIAALP
VFGIRYGLDM GTTALDDTPT GRATTALTTN FPAGALSPVE IIATGPGDTP LTGDPAAQVN
RFLAEIADDD RIDTVLPAQL NDGRVLALAL PSVAFDSMEA TDLIRDLRNT ATDAAGAEIR
IGGSTAEFVD LSDEMTSKLP LVVALVLTAS LIFLIAAFRS IALPIKAIAM NLLATGAALG
ITVAVFQWGL GENILDFTSP GFVQVYLPTV VFALLFGLSM DYEVFLIRRI REYWDTTGDN
EHAVAAGLTH TARPITAAAA IMIAIFASFL TADILELKQL GLALAVAVFL DAVLIRLVLV
PALMRLLGDW NWWLPTRPSI RPDTNTGI
//
