ID Q5YND8_NOCFA Unreviewed; 608 AA.
AC Q5YND8;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=Putative acyl-CoA dehydrogenase {ECO:0000313|EMBL:BAD60303.1};
GN Name=fadE49 {ECO:0000313|EMBL:BAD60303.1};
GN OrderedLocusNames=NFA_54510 {ECO:0000313|EMBL:BAD60303.1};
OS Nocardia farcinica (strain IFM 10152).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=247156 {ECO:0000313|EMBL:BAD60303.1, ECO:0000313|Proteomes:UP000006820};
RN [1] {ECO:0000313|EMBL:BAD60303.1, ECO:0000313|Proteomes:UP000006820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 10152 {ECO:0000313|EMBL:BAD60303.1,
RC ECO:0000313|Proteomes:UP000006820};
RX PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA Shiba T., Hattori M.;
RT "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|RuleBase:RU362125};
CC -!- SIMILARITY: Belongs to the acyl-CoA dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009347, ECO:0000256|RuleBase:RU362125}.
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DR EMBL; AP006618; BAD60303.1; -; Genomic_DNA.
DR RefSeq; WP_011211985.1; NC_006361.1.
DR AlphaFoldDB; Q5YND8; -.
DR STRING; 247156.NFA_54510; -.
DR GeneID; 61136023; -.
DR KEGG; nfa:NFA_54510; -.
DR eggNOG; COG1960; Bacteria.
DR HOGENOM; CLU_018204_12_1_11; -.
DR OrthoDB; 9807883at2; -.
DR Proteomes; UP000006820; Chromosome.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 2.40.110.20; -; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR025878; Acyl-CoA_dh-like_C_dom.
DR InterPro; IPR020953; Acyl-CoA_DH_N_bac.
DR InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009075; AcylCo_DH/oxidase_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR PANTHER; PTHR42803; ACYL-COA DEHYDROGENASE; 1.
DR PANTHER; PTHR42803:SF1; BROAD-SPECIFICITY LINEAR ACYL-COA DEHYDROGENASE FADE5; 1.
DR Pfam; PF00441; Acyl-CoA_dh_1; 1.
DR Pfam; PF12806; Acyl-CoA_dh_C; 1.
DR Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR Pfam; PF12418; AcylCoA_DH_N; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU362125};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU362125};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU362125};
KW Reference proteome {ECO:0000313|Proteomes:UP000006820}.
FT DOMAIN 3..34
FT /note="Acyl-CoA dehydrogenase N-terminal bacteria"
FT /evidence="ECO:0000259|Pfam:PF12418"
FT DOMAIN 162..271
FT /note="Acyl-CoA oxidase/dehydrogenase middle"
FT /evidence="ECO:0000259|Pfam:PF02770"
FT DOMAIN 288..454
FT /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00441"
FT DOMAIN 474..604
FT /note="Acetyl-CoA dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12806"
SQ SEQUENCE 608 AA; 66230 MW; D5878D9DEA0F1D96 CRC64;
MGHYKSNVRD LEFNLFEVLG LGSILDSGAY GDLDTDTVKE MLNEVRRLAE GPLGESFADA
DRNPPVFDPE THSVTLPESF KKSYKTLEEG GWDKFSVDEE LGGIKFPRTA YWAIAELILG
AQPAAFMYAA GAGFANIFYN NATEEQKKWA KIAVEQGWGA TMVLTEPDAG SDVGAGRTKA
IKQEDGSWHI EGVKRFITSA DSDDLFPNIM HLVLARPEGA GPGTKGLSLF FVPKFHFDPE
TGELGERNGV FVTNVEHKMG LKVSATCEVT FGGHGVPAKG WLVGEVHNGI AQMFEVIEHA
RMMVGTKAIA TLSTGYLNAL DYAKNRVQGA DLTQMTDKTA PRVTITHHPD VRRSLAMQKA
YAEGLRAVYL YTAAHQDVDV AAQVSGADAD LAARVNDLLL PIVKGVGSER AYQYLTESLQ
TFGGSGFLQD YPIEQYIRDA KIDSLYEGTT AIQAQDFFFR KIARDRGVAL AHVAGQVQKF
IDAESGNGRL KAERKLLATA LEDVQAMAAT LTGHLMGAQQ DPKELYKVGL GSVRFLLAVG
DLLIGWQLLR HAEVAIAALD NGSDEPFYHG KIATAQFFAR NVLPELTATR AILANLDNDI
MELDEAAF
//
