ID Q5YXK5_NOCFA Unreviewed; 287 AA.
AC Q5YXK5;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 118.
DE SubName: Full=Putative transcriptional regulator {ECO:0000313|EMBL:BAD57086.1};
GN OrderedLocusNames=NFA_22390 {ECO:0000313|EMBL:BAD57086.1};
OS Nocardia farcinica (strain IFM 10152).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=247156 {ECO:0000313|EMBL:BAD57086.1, ECO:0000313|Proteomes:UP000006820};
RN [1] {ECO:0000313|EMBL:BAD57086.1, ECO:0000313|Proteomes:UP000006820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 10152 {ECO:0000313|EMBL:BAD57086.1,
RC ECO:0000313|Proteomes:UP000006820};
RX PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA Shiba T., Hattori M.;
RT "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
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DR EMBL; AP006618; BAD57086.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5YXK5; -.
DR STRING; 247156.NFA_22390; -.
DR KEGG; nfa:NFA_22390; -.
DR eggNOG; COG1309; Bacteria.
DR eggNOG; COG1396; Bacteria.
DR HOGENOM; CLU_069356_12_4_11; -.
DR Proteomes; UP000006820; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR041490; KstR2_TetR_C.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR47506:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATOR YJDC; 1.
DR PANTHER; PTHR47506; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF17932; TetR_C_24; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Reference proteome {ECO:0000313|Proteomes:UP000006820};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 20..74
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT DOMAIN 98..158
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 121..140
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 287 AA; 31176 MW; 13CDE309CDCEBC77 CRC64;
MFGYSEHMDD RPTLPPHEAI RAARRAAGLS LRELARRIEV SPATLSAVEN GRTGLSVARL
ARLAEALGVS PARLLGGAPA VAPGRPAAEH GAWREFGPLD ADPVLTAAIA SFVDIGYHGT
TVRALADRAG TSVPGLYHRY RDKQDLLVRI LDLTMGELHW RVRAARAEGR DAVERVRLIV
EALALFHSHR RELGFIGASE MRSLLPADRA RIARSRTELQ HLLDEEIEAG RAAGLITTPH
PKAAGRAIAT MCTGIAQWFR ERGPATPEQI ATQYGEFALD LLGARPH
//
